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1631  structures 3131  species 15  interactions 34755  sequences 2750  architectures

Clan: Concanavalin (CL0004)

Summary

Concanavalin-like lectin/glucanase superfamily Add an annotation

This superfamily includes a diverse range of carbohydrate binding domains and glycosyl hydrolase enzymes that share a common structure.

This clan contains 16 families and the total number of domains in the clan is 34755. The clan was built by A Bateman.

Members

This clan contains the following 16 member families:

DUF1080 DUF2401 Gal-bind_lectin Glyco_hydro_11 Glyco_hydro_12 Glyco_hydro_16 Glyco_hydro_7 Laminin_G_1 Laminin_G_2 Laminin_G_3 Lectin_leg-like Lectin_legB Pentaxin Sialidase SKN1 Toxin_R_bind_N

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Laminin_G_2 (PF02210) 7915 (22.8%) View
Laminin_G_3 (PF13385) 6160 (17.7%) View
Glyco_hydro_7 (PF00840) 5196 (15.0%) View
Glyco_hydro_16 (PF00722) 4255 (12.2%) View
Gal-bind_lectin (PF00337) 2093 (6.0%) View
Lectin_legB (PF00139) 1651 (4.8%) View
Laminin_G_1 (PF00054) 1504 (4.3%) View
DUF1080 (PF06439) 1312 (3.8%) View
Pentaxin (PF00354) 1094 (3.1%) View
Glyco_hydro_11 (PF00457) 815 (2.3%) View
Lectin_leg-like (PF03388) 783 (2.3%) View
Sialidase (PF02973) 557 (1.6%) View
Glyco_hydro_12 (PF01670) 532 (1.5%) View
SKN1 (PF03935) 512 (1.5%) View
Toxin_R_bind_N (PF07953) 203 (0.6%) View
DUF2401 (PF10287) 173 (0.5%) View
Total: 16 Total: 34755 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 15 interactions for this clan. More...

Interacting families
A B
Lectin_legB Lectin_legB
Laminin_G_2 Laminin_G_2
V-set
Lectin_leg-like Lectin_leg-like
Laminin_G_1 Laminin_G_1
Gal-bind_lectin Gal-bind_lectin
Glyco_hydro_11 Glyco_hydro_11
Glyco_hydro_18
CBM_6
Toxin_R_bind_N Toxin_R_bind_C
Toxin_trans
Glyco_hydro_16 Glyco_hydro_16
XET_C
Pentaxin Pentaxin
Glyco_hydro_12 Glyco_hydro_12

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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