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581  structures 748  species 10  interactions 15749  sequences 825  architectures

Clan: C_Lectin (CL0056)

Summary

C-type lectin-like superfamily Add an annotation

This clan contains domains that have a C-type lectin fold. Many of these are known or expected to mediate interactions with sugars.

This clan contains 7 families and the total number of domains in the clan is 15749. The clan was built by A Bateman.

Members

This clan contains the following 7 member families:

APT C4 Chordopox_A33R Herpes_UL45 Intimin_C Lectin_C Xlink

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Lectin_C (PF00059) 12227 (77.6%) View
Xlink (PF00193) 1651 (10.5%) View
C4 (PF01413) 1172 (7.4%) View
Intimin_C (PF07979) 389 (2.5%) View
Herpes_UL45 (PF05473) 167 (1.1%) View
APT (PF03440) 77 (0.5%) View
Chordopox_A33R (PF05966) 66 (0.4%) View
Total: 7 Total: 15749 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 10 interactions for this clan. More...

Interacting families
A B
Xlink Xlink
Lectin_C EGF
fn3
Lectin_C
VWA
MHC_I
C1-set
Surfac_D-trimer
Intimin_C Big_2
C4 C4

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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