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181  structures 2623  species 3  interactions 7651  sequences 97  architectures

Clan: DNA_pol_B-like (CL0194)

Summary

DNA polymerase B like Add an annotation

DNA polymerases replicate DNA by adding nucleotide triphosphate (dNTP) residues to the 5'-end of a growing chain of DNA. They use a complementary DNA chain as a template.`

This clan contains 4 families and the total number of domains in the clan is 7651. The clan was built by J Mistry.

Literature references

  1. Zhou M, Mao C, Rodriguez AC, Kiefer JR, Kucera RB, Beese LS; , Acta Crystallogr D Biol Crystallogr 1998;54:994-995.: Crystallization and preliminary diffraction analysis of a hyperthermostable DNA polymerase from a Thermococcus archaeon. PUBMED:9757117 EPMC:9757117

Members

This clan contains the following 4 member families:

DNA_pol_B DNA_pol_B_2 DUF1744 Pox_F12L

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
DNA_pol_B (PF00136) 6234 (81.5%) View
DNA_pol_B_2 (PF03175) 975 (12.7%) View
DUF1744 (PF08490) 355 (4.6%) View
Pox_F12L (PF03337) 87 (1.1%) View
Total: 4 Total: 7651 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
DNA_pol_B_2 DNA_pol_B_2
DNA_pol_B DNA_pol_B
DNA_pol_B_exo1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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