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475  structures 5545  species 12  interactions 154594  sequences 3478  architectures

Clan: CheY (CL0304)

Summary

CheY-like superfamily Add an annotation

This clan includes the CheY-like response regulators from bacteria [1-2].

This clan contains 3 families and the total number of domains in the clan is 154594. The clan was built by A Bateman.

Literature references

  1. Pao GM, Saier MH; , J Mol Evol 1995;40:136-154.: Response regulators of bacterial signal transduction systems: selective domain shuffling during evolution. PUBMED:7699720 EPMC:7699720
  2. Galperin MY; , J Bacteriol. 2006;188:4169-4182.: Structural classification of bacterial response regulators: diversity of output domains and domain combinations. PUBMED:16740923 EPMC:16740923

Members

This clan contains the following 3 member families:

FleQ OKR_DC_1_N Response_reg

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Response_reg (PF00072) 151337 (97.9%) View
OKR_DC_1_N (PF03709) 2923 (1.9%) View
FleQ (PF06490) 334 (0.2%) View
Total: 3 Total: 154594 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 12 interactions for this clan. More...

Interacting families
A B
OKR_DC_1_N OKR_DC_1
Response_reg Response_reg
Sigma54_activat
GerE
Trans_reg_C
GGDEF
CheB_methylest
Hpt
ANTAR
CheZ
CheY-binding
RcsC

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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