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345  structures 4003  species 13  interactions 18678  sequences 276  architectures

Clan: GHD (CL0369)

Summary

Glycosyl hydrolase domain superfamily Add an annotation

This domain is C-terminal to the catalytic beta/alpha barrel domain. The superfamily includes the C-terminal domain of a number of sugar-lytic families.

This clan contains 8 families and the total number of domains in the clan is 18678. The clan was built by A Bateman.

Members

This clan contains the following 8 member families:

Alpha-amylase_C CBM_20 CBM_48 Cyc-maltodext_C DUF1939 DUF1966 DUF3459 Glyco_hydro_42C

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
CBM_48 (PF02922) 8560 (45.8%) View
Alpha-amylase_C (PF02806) 4792 (25.7%) View
DUF3459 (PF11941) 2445 (13.1%) View
CBM_20 (PF00686) 1301 (7.0%) View
Glyco_hydro_42C (PF08533) 633 (3.4%) View
DUF1939 (PF09154) 520 (2.8%) View
DUF1966 (PF09260) 219 (1.2%) View
Cyc-maltodext_C (PF10438) 208 (1.1%) View
Total: 8 Total: 18678 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 13 interactions for this clan. More...

Interacting families
A B
Cyc-maltodext_C Alpha-amylase
Glyco_hydro_42C Glyco_hydro_42
Glyco_hydro_42M
DUF1939 Alpha-amylase
CBM_20 Alpha-amylase
CBM_20
Glyco_hydro_14
TIG
DUF1966 Alpha-amylase
Alpha-amylase_C Alpha-amylase
TIG
Alpha-amylase_C
CBM_48 Alpha-amylase

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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