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310  structures 4947  species 3  interactions 18056  sequences 183  architectures

Clan: Cyclophil-like (CL0475)

Summary

Cyclophilin-like superfamily Add an annotation

This superfamily is characterised by being the core, closed, beta barrel of cyclophilin with complex topology, with some family members lacking the N-terminal strand of cyclophilin but retaining a closed barrel.

This clan contains 6 families and the total number of domains in the clan is 18056. The clan was built by P Coggill.

Members

This clan contains the following 6 member families:

AHS1 Cyclophil_like DUF3830 DUF871 PIF Pro_isomerase

External database links

Domain organisation

Below is a listing of the unique domain organisations or architectures from this clan. More...

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Alignments

The table below shows the number of occurrences of each domain throughout the sequence database. More...

Pfam family Num. domains Alignment
Pro_isomerase (PF00160) 13237 (73.3%) View
AHS1 (PF02682) 3092 (17.1%) View
DUF871 (PF05913) 1290 (7.1%) View
Cyclophil_like (PF04126) 235 (1.3%) View
DUF3830 (PF12903) 130 (0.7%) View
PIF (PF05092) 72 (0.4%) View
Total: 6 Total: 18056 Clan alignment
 

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Family relationships

This diagram shows the relationships between members of this clan. More...

Species distribution

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This tree shows the occurrence of the domains in this clan across different species. More...

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Interactions

There are 3 interactions for this clan. More...

Interacting families
A B
Cyclophil_like Cyclophil_like
Pro_isomerase Pro_isomerase
PRP4

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between the Pfam families in this clan, the corresponding UniProt entries, and the region of the three-dimensional structures that are available for that sequence.

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