Summary: Cor1/Xlr/Xmr conserved region
Cor1/Xlr/Xmr conserved region Provide feedback
Cor1 is a component of the chromosome core in the meiotic prophase chromosomes . Xlr is a lymphoid cell specific protein . Xlm is abundantly transcribed in testis in a tissue-specific and developmentally regulated manner. The protein is located in the nuclei of spermatocytes, early in the prophase of the first meiotic division, and later becomes concentrated in the XY nuclear subregion where it is in particular associated with the axes of sex chromosomes .
Dobson MJ, Pearlman RE, Karaiskakis A, Spyropoulos B, Moens PB; , J Cell Sci 1994;107:2749-2760.: Synaptonemal complex proteins: occurrence, epitope mapping and chromosome disjunction. PUBMED:7876343 EPMC:7876343
Bergsagel PL, Timblin CR, Kozak CA, Kuehl WM; , Gene 1994;150:345-350.: Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily. PUBMED:7821804 EPMC:7821804
Calenda A, Allenet B, Escalier D, Bach JF, Garchon HJ; , EMBO J 1994;13:100-109.: The meiosis-specific Xmr gene product is homologous to the lymphocyte Xlr protein and is a component of the XY body. PUBMED:8306953 EPMC:8306953
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR006888Cor1 is a component of the chromosome core in the meiotic prophase chromosomes [PUBMED:7876343]. Xlr is a lymphoid cell specific protein [PUBMED:7821804]. Xmr is abundantly transcribed in testis in a tissue-specific and developmentally regulated manner. The protein is located in the nuclei of spermatocytes, early in the prophase of the first meiotic division, and later becomes concentrated in the XY nuclear subregion where it is in particular associated with the axes of sex chromosomes [PUBMED:8306953].
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Curation and family details
|Seed source:||Pfam-B_6320 (release 7.5)|
|Author:||Waterfield DI, Finn RD|
|Number in seed:||12|
|Number in full:||157|
|Average length of the domain:||115.40 aa|
|Average identity of full alignment:||34 %|
|Average coverage of the sequence by the domain:||52.16 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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