Summary: Actinobacillus actinomycetemcomitans leukotoxin activator LktC
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This family consists of several Actinobacillus actinomycetemcomitans leukotoxin activator (LktC) proteins. Actinobacillus actinomycetemcomitans is a Gram-negative bacterium that has been implicated in the etiology of several forms of periodontitis, especially localised juvenile periodontitis. LktC along with LktB and LktD are thought to be required for activation and localisation of the leukotoxin .
Spitznagel J Jr, Kraig E, Kolodrubetz D; , Infect Immun 1991;59:1394-1401.: Regulation of leukotoxin in leukotoxic and nonleukotoxic strains of Actinobacillus actinomycetemcomitans. PUBMED:2004819 EPMC:2004819
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR009369
This family consists of several Actinobacillus actinomycetemcomitans leukotoxin activator (LktC) proteins. Actinobacillus actinomycetemcomitans is a Gram-negative bacterium that has been implicated in the etiology of several forms of periodontitis, especially localised juvenile periodontitis. LktC along with LktB and LktD are thought to be required for activation and localisation of the leukotoxin [PUBMED:2004819].
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Curation and family details
|Seed source:||Pfam-B_11552 (release 9.0)|
|Number in seed:||2|
|Number in full:||18|
|Average length of the domain:||139.60 aa|
|Average identity of full alignment:||91 %|
|Average coverage of the sequence by the domain:||99.45 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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