Summary: BRCA1-associated protein 2
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These proteins include BRCA1-associated protein 2 (BRAP2), which binds nuclear localisation signals (NLSs) in vitro and in yeast two-hybrid screening . These proteins share a region of sequence similarity at their N terminus. They also have PF02148 at the C terminus.
Li S, Ku CY, Farmer AA, Cong YS, Chen CF, Lee WH; , J Biol Chem 1998;273:6183-6189.: Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs. PUBMED:9497340 EPMC:9497340
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR011422
These proteins include BRCA1-associated protein 2 (BRAP2), which binds nuclear localisation signals (NLSs) in vitro and in yeast two-hybrid screening [PUBMED:9497340]. These proteins share a region of sequence similarity at their N terminus. They also have INTERPRO at the C terminus.
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This clan contains families that are related to the RNA recognition motif domains. However, not all these families are RNA binding.
The clan contains the following 15 members:BRAP2 Calcipressin DUF1866 Limkain-b1 Nup35_RRM Nup35_RRM_2 Ribosomal_L23 RNA_bind RRM_1 RRM_2 RRM_3 RRM_5 RRM_6 Smg4_UPF3 XS
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Curation and family details
|Seed source:||Pfam-B_5419 (release 11.0)|
|Author:||Studholme DJ, Wood V|
|Number in seed:||8|
|Number in full:||297|
|Average length of the domain:||104.60 aa|
|Average identity of full alignment:||28 %|
|Average coverage of the sequence by the domain:||17.78 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||7|
|Download:||download the raw HMM for this family|
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