Summary: Diapausin family of antimicrobial peptide
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Diapausin family of antimicrobial peptide Provide feedback
This family consists of diapausin-related antimicrobial peptides. Diapause during periods of environmental adversity is an essential part of the life cycle of many organisms with the molecular basis being different among animals. Diapause-specific peptides provide anti-fungal activity and act as N-type voltage-gated calcium channel blocker .
Tanaka H, Sato K, Saito Y, Yamashita T, Agoh M, Okunishi J, Tachikawa E, Suzuki K; , Peptides 2003;24:1327-1333.: Insect diapause-specific peptide from the leaf beetle has consensus with a putative iridovirus peptide. PUBMED:14706547 EPMC:14706547
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR012525
This family consists of diapausin-related antimicrobial peptides. Diapause during periods of environmental adversity is an essential part of the life cycle of many organisms with the molecular basis being different among animals. Diapause-specific peptides provide anti-fungal activity and act as N-type voltage-gated calcium channel blocker [PUBMED:14706547].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Cellular component||extracellular region (GO:0005576)|
|Biological process||defense response to fungus (GO:0050832)|
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This example describes an architecture with one
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Curation and family details
|Seed source:||Short protein clustering|
|Number in seed:||3|
|Number in full:||10|
|Average length of the domain:||39.60 aa|
|Average identity of full alignment:||52 %|
|Average coverage of the sequence by the domain:||63.36 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe group, to allow us to map Pfam domains onto UniProt sequences and three-dimensional protein structures. The table below shows the structures on which the Antimicrobial_6 domain has been found. There are 1 instances of this domain found in the PDB. Note that there may be multiple copies of the domain in a single PDB structure, since many structures contain multiple copies of the same protein seqence.
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