Summary: Influenza Matrix protein (M1) C-terminal domain
Influenza Matrix protein (M1) C-terminal domain Provide feedback
This region is thought to be a second domain of the M1 matrix protein.
Okada A, Miura T, Takeuchi H; , Biochemistry 2003;42:1978-1984.: Zinc- and pH-dependent conformational transition in a putative interdomain linker region of the influenza virus matrix protein M1. PUBMED:12590584 EPMC:12590584
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR013188
Matrix protein (M1) of Influenza virus is a bifunctional membrane/RNA-binding protein that mediates the encapsidation of RNA-nucleoprotein cores into the membrane envelope. It is therefore required that M1 binds both membrane and RNA simultaneously. M1 is comprised of two domains connected by a linker sequence. The C-terminal domain contains alpha-helical structure and appears to be involved in growth and virulence of the virus [PUBMED:15892972, PUBMED:12590584].
The mapping between Pfam and Gene Ontology is provided by InterPro. If you use this data please cite InterPro.
|Molecular function||RNA binding (GO:0003723)|
|structural molecule activity (GO:0005198)|
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This example describes an architecture with one
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EGFdomains, and finally a single
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Curation and family details
|Seed source:||Pfam-B_30 (Release 17.0)|
|Number in seed:||2|
|Number in full:||22741|
|Average length of the domain:||94.30 aa|
|Average identity of full alignment:||91 %|
|Average coverage of the sequence by the domain:||38.38 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||6|
|Download:||download the raw HMM for this family|
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