Summary: Phage terminase small subunit
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Phage terminase small subunit Provide feedback
This family of small highly conserved proteins come from a subset of Firmicute species. Its putative function is as a phage terminase small subunit.
Rao VB, Black LW; , J Mol Biol. 1988;200:475-488.: Cloning, overexpression and purification of the terminase proteins gp16 and gp17 of bacteriophage T4. Construction of a defined in-vitro DNA packaging system using purified terminase proteins. PUBMED:3294420 EPMC:3294420
Internal database links
|SCOOP:||HTH_Tnp_1_2 DUF4633 Phage_CII|
|Similarity to PfamA using HHSearch:||GerE HTH_7 MerR HTH_Tnp_1 Terminase_5 HTH_11 Sigma70_r4_2 HTH_17 HTH_23 HTH_28 HTH_38|
External database links
This tab holds annotation information from the InterPro database.
InterPro entry IPR018925
This entry describes the terminase small subunit from Enterococcus phage phiFL1A, related proteins in other bacteriophage, and prophage regions of bacterial genomes.
Packaging of double-stranded viral DNA concatemers requires interaction of the prohead with virus DNA. This process is mediated by a phage-encoded DNA recognition and terminase protein. The terminase enzymes described so far, which are hetero-oligomers composed of a small and a large subunit, do not have a significant level of sequence homology. The small terminase subunit is thought to form a nucleoprotein structure that helps to position the terminase large subunit at the packaging initiation site [PUBMED:2679356].
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Curation and family details
|Seed source:||FIG022212 (Release 2.0)|
|Author:||FIGfams, Mistry J, Coggill P|
|Number in seed:||6|
|Number in full:||212|
|Average length of the domain:||60.70 aa|
|Average identity of full alignment:||37 %|
|Average coverage of the sequence by the domain:||24.56 %|
|HMM build commands:||
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
|Family (HMM) version:||4|
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