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0  structures 71  species 0  interactions 129  sequences 1  architecture

Family: CCDC50_N (PF15295)

Summary: Coiled-coil domain-containing protein 50 N-terminus

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This is the Wikipedia entry entitled "CCDC50". More...

CCDC50 Edit Wikipedia article

Coiled-coil domain containing 50
Identifiers
Symbols CCDC50; C3orf6; DFNA44; YMER
External IDs OMIM611051 HomoloGene32655 GeneCards: CCDC50 Gene
Orthologs
Species Human Mouse
Entrez 152137 n/a
Ensembl ENSG00000152492 n/a
UniProt Q8IVM0 n/a
RefSeq (mRNA) NM_174908 n/a
RefSeq (protein) NP_777568 n/a
Location (UCSC) Chr 3:
191.05 – 191.12 Mb
n/a
PubMed search [1] n/a

Coiled-coil domain-containing protein 50 is a protein that in humans is encoded by the CCDC50 gene.[1][2][3]

References[edit]

  1. ^ Vazza G, Picelli S, Bozzato A, Mostacciuolo ML (Oct 2003). "Identification and characterization of C3orf6, a new conserved human gene mapping to chromosome 3q28". Gene 314: 113–20. doi:10.1016/S0378-1119(03)00710-8. PMID 14527723. 
  2. ^ Tashiro K, Konishi H, Sano E, Nabeshi H, Yamauchi E, Taniguchi H (Aug 2006). "Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein". J Biol Chem 281 (34): 24612–22. doi:10.1074/jbc.M604184200. PMID 16803894. 
  3. ^ "Entrez Gene: CCDC50 coiled-coil domain containing 50". 

Further reading[edit]


This page is based on a Wikipedia article. The text is available under the Creative Commons Attribution/Share-Alike License.

This tab holds the annotation information that is stored in the Pfam database. As we move to using Wikipedia as our main source of annotation, the contents of this tab will be gradually replaced by the Wikipedia tab.

Coiled-coil domain-containing protein 50 N-terminus Provide feedback

No Pfam abstract.

Literature references

  1. Vazza G, Picelli S, Bozzato A, Mostacciuolo ML;, Gene. 2003;314:113-120.: Identification and characterization of C3orf6, a new conserved human gene mapping to chromosome 3q28. PUBMED:14527723 EPMC:14527723


External database links

This tab holds annotation information from the InterPro database.

No InterPro data for this Pfam family.

Domain organisation

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Alignments

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We make a range of alignments for each Pfam-A family. You can see a description of each above. You can view these alignments in various ways but please note that some types of alignment are never generated while others may not be available for all families, most commonly because the alignments are too large to handle.

  Seed
(11)
Full
(129)
Representative proteomes NCBI
(106)
Meta
(0)
RP15
(13)
RP35
(22)
RP55
(50)
RP75
(74)
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Key: ✓ available, x not generated, not available.

Format an alignment

  Seed
(11)
Full
(129)
Representative proteomes NCBI
(106)
Meta
(0)
RP15
(13)
RP35
(22)
RP55
(50)
RP75
(74)
Alignment:
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Order:
Sequence:
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We make all of our alignments available in Stockholm format. You can download them here as raw, plain text files or as gzip-compressed files.

  Seed
(11)
Full
(129)
Representative proteomes NCBI
(106)
Meta
(0)
RP15
(13)
RP35
(22)
RP55
(50)
RP75
(74)
Raw Stockholm Download   Download   Download   Download   Download   Download   Download    
Gzipped Download   Download   Download   Download   Download   Download   Download    

You can also download a FASTA format file containing the full-length sequences for all sequences in the full alignment.

External links

MyHits provides a collection of tools to handle multiple sequence alignments. For example, one can refine a seed alignment (sequence addition or removal, re-alignment or manual edition) and then search databases for remote homologs using HMMER3.

Pfam alignments:

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Curation and family details

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This family is new in this Pfam release.

Seed source: Jackhmmer:Q8IVM0
Previous IDs: none
Type: Family
Author: Eberhardt RY, Coggill P, Hetherington K
Number in seed: 11
Number in full: 129
Average length of the domain: 127.30 aa
Average identity of full alignment: 47 %
Average coverage of the sequence by the domain: 30.86 %

HMM information View help on HMM parameters

HMM build commands:
build method: hmmbuild -o /dev/null HMM SEED
search method: hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
Model details:
Parameter Sequence Domain
Gathering cut-off 27.0 27.0
Trusted cut-off 27.0 29.3
Noise cut-off 22.0 24.6
Model length: 132
Family (HMM) version: 1
Download: download the raw HMM for this family

Species distribution

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