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Browse Pfam families

New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
ID Accession Type Number of sequences Average length Average %id Average coverage Has 3D Change status Description
Seed Full
I-set PF07679 Domain 48 59728 88.50 21 29.33 Changed Immunoglobulin I-set domain
IalB PF06776 Family 84 752 127.70 25 66.93 Changed Invasion associated locus B (IalB) protein
IATP PF04568 Family 34 329 83.00 28 76.51 Changed Mitochondrial ATPase inhibitor, IATP
IBB PF01749 Family 18 914 92.30 32 18.60 Changed Importin beta binding domain
IBD PF10416 Domain 94 107 122.10 22 48.18 Changed Transcription-initiator DNA-binding domain IBD
IBN_N PF03810 Domain 52 2930 72.40 20 7.63 Changed Importin-beta N-terminal domain
IBP39 PF11422 Family 7 7 181.70 26 53.63 Changed Initiator binding protein 39 kDa
IBR PF01485 Family 166 4521 66.80 23 18.68 Changed IBR domain
Ibs_toxin PF13956 Family 4 33 18.80 77 64.41 Changed Toxin Ibs, type I toxin-antitoxin system
IBV_3A PF03617 Family 6 81 56.80 82 99.74 Changed IBV 3A protein
IBV_3B PF03622 Family 7 88 63.20 73 99.30 Changed IBV 3B protein
IBV_3C PF03620 Family 3 126 92.10 87 87.33 Changed IBV 3C protein
ICA69 PF04629 Domain 6 145 173.60 37 43.48 Changed Islet cell autoantigen ICA69, C-terminal domain
ICAM_N PF03921 Family 5 218 89.10 36 19.09 Changed Intercellular adhesion molecule (ICAM), N-terminal domain
ICAP-1_inte_bdg PF10480 Family 2 77 168.10 64 91.50 Changed Beta-1 integrin binding protein
ICAT PF06384 Family 8 132 76.50 47 44.90 Changed Beta-catenin-interacting protein ICAT
ICE2 PF08426 Family 16 140 388.20 36 93.55 Changed ICE2
ICEA PF05315 Family 2 70 165.40 58 93.91 Changed ICEA Protein
IceA2 PF05862 Family 2 35 51.90 64 104.66 Changed Helicobacter pylori IceA2 protein
Ice_nucleation PF00818 Repeat 110 1266 15.80 74 44.84 Changed Ice nucleation protein repeat
ICL PF00463 Domain 7 4174 225.10 28 93.61 Changed Isocitrate lyase family
IclR PF01614 Family 23 10733 124.00 23 46.91 Changed Bacterial transcriptional regulator
IcmF-related PF06761 Family 95 1440 297.20 22 27.04 Changed Intracellular multiplication and human macrophage-killing
IcmL PF11393 Family 23 289 101.70 27 48.53 Changed Macrophage killing protein with similarity to conjugation protein
ICMT PF04140 Family 12 1448 94.30 31 44.00 Changed Isoprenylcysteine carboxyl methyltransferase (ICMT) family
IDEAL PF08858 Domain 42 993 36.70 34 26.17 Changed IDEAL domain
IDH PF03971 Family 5 1265 682.90 61 98.77 Changed Monomeric isocitrate dehydrogenase
IDO PF01231 Family 39 516 358.10 28 79.96 Changed Indoleamine 2,3-dioxygenase
IER PF05760 Family 10 171 176.10 27 97.89 Changed Immediate early response protein (IER)
IF-2 PF11987 Domain 243 5391 108.80 42 13.02 Changed Translation-initiation factor 2
IF-2B PF01008 Family 18 3047 282.00 28 77.40 Changed Initiation factor 2 subunit family
IF2_assoc PF08364 Family 89 1458 40.90 51 4.66 Changed Bacterial translation initiation factor IF-2 associated region
IF2_N PF04760 Family 141 7695 52.00 26 10.04 Changed Translation initiation factor IF-2, N-terminal region
IF3_C PF00707 Domain 150 4680 87.80 44 49.92 Changed Translation initiation factor IF-3, C-terminal domain
IF3_N PF05198 Domain 181 4308 67.60 52 37.87 Changed Translation initiation factor IF-3, N-terminal domain
IF4E PF01652 Domain 135 1579 157.30 32 65.03 Changed Eukaryotic initiation factor 4E
Ifi-6-16 PF06140 Family 27 261 77.60 48 56.27 Changed Interferon-induced 6-16 family
IFN-gamma PF00714 Domain 9 229 123.10 50 85.86 Changed Interferon gamma
IFNGR1 PF07140 Family 12 134 134.40 36 41.50 Changed Interferon gamma receptor (IFNGR1)
IFP_35_N PF07334 Family 6 78 71.60 41 25.89 Changed Interferon-induced 35 kDa protein (IFP 35) N-terminus
IFR3_antag PF14754 Domain 2 79 249.00 97 12.89 New Papain-like auto-proteinase
IFRD PF05004 Family 7 396 275.60 27 66.11 Changed Interferon-related developmental regulator (IFRD)
IFRD_C PF04836 Family 13 196 54.50 53 13.18 Changed Interferon-related protein conserved region
IFT20 PF14931 Family 26 146 114.40 42 85.21 New Intraflagellar transport complex B, subunit 20
IFT43 PF15305 Family 34 125 137.10 37 64.49 New Intraflagellar transport protein 43
IFT46_B_C PF12317 Family 13 166 199.20 49 58.91 Changed Intraflagellar transport complex B protein 46 C terminal
IFT57 PF10498 Family 18 178 298.40 38 81.42 Changed Intra-flagellar transport protein 57
ig PF00047 Domain 52 1594 63.00 21 11.35 Changed Immunoglobulin domain
IgaA PF07095 Family 10 600 641.80 75 99.32 Changed Intracellular growth attenuator protein IgaA
IGF2_C PF08365 Family 8 168 53.80 62 28.71 Changed Insulin-like growth factor II E-peptide
IGFBP PF00219 Domain 54 1051 54.50 44 18.34 Changed Insulin-like growth factor binding protein
IGFL PF14653 Family 9 151 68.80 44 82.70 New Insulin growth factor-like family
IgG_binding_B PF01378 Domain 4 50 53.60 73 27.86 Changed B domain
IglC PF11550 Family 2 33 203.70 95 100.00 Changed Intracellular growth locus C protein
IGPD PF00475 Family 146 3695 144.30 51 57.73 Changed Imidazoleglycerol-phosphate dehydratase
IGPS PF00218 Domain 20 5164 228.50 40 76.40 Changed Indole-3-glycerol phosphate synthase
IGR PF09597 Domain 18 185 56.80 39 30.06 Changed IGR protein motif
Ig_2 PF13895 Domain 70 24350 89.10 15 18.46 Changed Immunoglobulin domain
Ig_3 PF13927 Domain 182 4712 77.20 17 13.25 Changed Immunoglobulin domain
Ig_J_chain PF15097 Family 4 36 126.70 71 78.70 New Immunoglobulin J chain
Ig_Tie2_1 PF10430 Domain 4 53 95.50 79 9.53 Changed Tie-2 Ig-like domain 1
IIGP PF05049 Family 6 355 294.00 31 78.44 Changed Interferon-inducible GTPase (IIGP)
IKI3 PF04762 Family 34 404 666.90 27 69.81 Changed IKI3 family
IKKbetaNEMObind PF12179 Domain 9 110 37.60 47 5.40 Changed I-kappa-kinase-beta NEMO binding domain
IL1 PF00340 Domain 16 589 110.80 26 54.99 Changed Interleukin-1 / 18
IL10 PF00726 Domain 3 341 146.60 36 93.10 Changed Interleukin 10
IL11 PF07400 Family 3 55 175.50 46 79.67 Changed Interleukin 11
IL12 PF03039 Domain 3 97 172.50 47 88.05 Changed Interleukin-12 alpha subunit
IL12p40_C PF10420 Domain 21 132 87.30 42 29.28 Changed Cytokine interleukin-12p40 C-terminus
IL13 PF03487 Family 4 47 42.00 77 32.90 Changed Interleukin-13
IL15 PF02372 Family 14 168 126.90 31 84.55 Changed Interleukin 15
IL17 PF06083 Family 20 312 81.80 39 48.52 Changed Interleukin-17
IL17_R_N PF15037 Family 7 139 299.40 33 61.25 New Interleukin-17 receptor extracellular region
IL1_propep PF02394 Family 23 206 96.10 34 38.57 Changed Interleukin-1 propeptide
IL2 PF00715 Domain 7 151 124.30 65 94.53 Changed Interleukin 2
IL22 PF14565 Domain 5 53 136.60 54 77.25 New Interleukin 22 IL-10-related T-cell-derived-inducible factor
IL28A PF15177 Family 10 96 145.40 55 79.55 New Interleukin-28A
IL3 PF02059 Family 5 41 113.60 47 79.56 Changed Interleukin-3
IL31 PF15209 Family 4 23 131.70 46 85.76 New Interleukin 31
IL32 PF15225 Family 2 18 92.30 85 50.78 New Interleukin 32
IL33 PF15095 Family 4 41 204.20 59 97.66 New Interleukin 33
IL34 PF15036 Domain 5 39 160.20 69 72.21 New Interleukin 34
IL4 PF00727 Domain 8 198 84.40 48 78.13 Changed Interleukin 4
IL4Ra_N PF09238 Domain 7 71 90.20 45 18.27 Changed Interleukin-4 receptor alpha chain, N-terminal
IL5 PF02025 Domain 6 60 105.40 63 84.89 Changed Interleukin 5
IL6 PF00489 Domain 10 256 135.50 31 71.80 Changed Interleukin-6/G-CSF/MGF family
IL6Ra-bind PF09240 Domain 23 523 94.90 22 19.27 Changed Interleukin-6 receptor alpha chain, binding
IL7 PF01415 Family 7 77 111.60 42 85.17 Changed Interleukin 7/9 family
IL8 PF00048 Domain 181 2117 63.80 25 56.48 Changed Small cytokines (intecrine/chemokine), interleukin-8 like
Ilar_coat PF01787 Family 20 499 189.10 34 91.67 Changed Ilarvirus coat protein
Ilm1 PF10311 Family 22 113 171.60 30 86.20 Changed Increased loss of mitochondrial DNA protein 1
IlvB_leader PF08049 Family 4 116 31.90 83 99.14 Changed IlvB leader peptide
IlvC PF01450 Family 19 5123 141.90 39 46.51 Changed Acetohydroxy acid isomeroreductase, catalytic domain
ILVD_EDD PF00920 Family 89 6864 522.70 40 91.02 Changed Dehydratase family
IlvGEDA_leader PF08046 Family 2 92 31.90 94 95.19 Changed IlvGEDA operon leader peptide
IlvN PF07991 Family 45 4225 165.30 49 44.30 Changed Acetohydroxy acid isomeroreductase, catalytic domain
Ima1_N PF09779 Family 12 204 120.30 35 19.20 Changed Ima1 N-terminal domain
ImcF-related_N PF14331 Family 110 1314 257.20 27 22.64 Changed ImcF-related N-terminal domain
IMCp PF12314 Family 22 202 80.50 33 25.71 Changed Inner membrane complex protein
IMD PF08397 Family 8 584 190.70 31 31.80 Changed IRSp53/MIM homology domain
Img2 PF05046 Domain 22 279 82.20 32 50.39 Changed Mitochondrial large subunit ribosomal protein (Img2)
Imm-NTF2 PF15655 Family 32 92 130.10 21 66.80 New NTF2 fold immunity protein
Imm-NTF2-2 PF15631 Family 17 170 67.30 70 58.81 New NTF2 fold immunity protein
Imm1 PF14430 Family 26 58 125.30 16 90.44 Changed Immunity protein Imm1
Imm10 PF15562 Family 46 149 59.30 30 73.33 New Immunity protein 10
Imm11 PF15563 Family 3 9 221.80 47 96.85 New Immunity protein 11
Imm12 PF15589 Family 17 45 144.10 33 88.74 New Immunity protein 12
Imm13 PF15564 Family 2 3 131.00 66 79.39 New Immunity protein 13
Imm14 PF15428 Family 70 172 121.50 18 51.88 New Immunity protein 14
Imm15 PF15590 Family 5 9 69.80 37 13.46 New Immunity protein 15
Imm16 PF15565 Family 6 55 98.40 38 65.46 New Immunity protein 16
Imm17 PF15591 Family 6 26 77.40 76 97.53 New Immunity protein 17
Imm18 PF15566 Family 9 13 52.50 36 65.01 New Immunity protein 18
Imm19 PF15567 Family 20 224 85.00 73 70.53 New Immunity protein 19
Imm2 PF14426 Family 5 9 59.30 46 73.66 Changed Immunity protein Imm2
Imm20 PF15568 Family 2 3 96.70 50 94.16 New Immunity protein 20
Imm21 PF15569 Family 11 48 84.30 53 77.70 New Immunity protein 21
Imm22 PF15592 Family 13 133 110.90 58 90.11 New Immunity protein 22
Imm23 PF15593 Family 26 70 150.50 23 94.87 New Immunity protein 23
Imm24 PF15570 Family 11 23 119.60 29 55.27 New Immunity protein 24
Imm25 PF15571 Family 3 30 125.40 37 95.19 New Immunity protein 25
Imm26 PF15572 Family 19 24 95.40 35 75.88 New Immunity protein 26
Imm27 PF15573 Family 10 46 234.00 55 96.89 New Immunity protein 27
Imm28 PF15574 Family 8 15 117.70 43 93.88 New Immunity protein 28
Imm29 PF15575 Family 81 217 198.40 19 70.51 New Immunity protein 29
Imm3 PF14425 Family 26 52 116.30 55 95.29 Changed Immunity protein Imm3
Imm30 PF15594 Family 40 70 120.60 23 86.37 New Immunity protein 30
Imm31 PF15595 Family 33 97 106.30 27 70.46 New Immunity protein 31
Imm32 PF15579 Family 36 138 95.40 43 46.47 New Immunity protein 32
Imm33 PF15580 Family 33 42 89.90 36 81.91 New Immunity protein 33
Imm34 PF15596 Family 3 76 91.60 92 74.39 New Immunity protein 34
Imm35 PF15581 Family 4 5 93.00 41 86.43 New Immunity protein 35
Imm36 PF15597 Family 31 66 92.00 35 93.27 New Immunity protein 36
Imm37 PF15598 Family 27 97 153.10 32 84.76 New Immunity protein 37
Imm38 PF15599 Family 30 130 116.40 27 77.94 New Immunity protein 38
Imm39 PF15600 Family 8 16 175.80 43 95.36 New Immunity protein 39
Imm40 PF15582 Family 2 16 222.90 40 87.58 New Immunity protein 40
Imm41 PF15583 Family 13 63 147.30 48 27.96 New Immunity protein 41
Imm42 PF15601 Family 33 74 125.60 35 92.37 New Immunity protein 42
Imm43 PF15602 Family 15 39 171.40 31 51.90 New Immunity protein 43
Imm44 PF15584 Family 17 44 100.50 46 32.10 New Immunity protein 44
Imm45 PF15603 Family 16 55 75.10 44 98.95 New Immunity protein 45
Imm46 PF15585 Family 17 27 115.60 35 94.69 New Immunity protein 46
Imm47 PF15586 Family 29 121 107.40 38 93.43 New Immunity protein 47
Imm48 PF15587 Family 7 30 153.90 43 97.65 New Immunity protein 48
Imm49 PF15660 Family 4 10 82.90 99 96.96 New Immunity protein 49
Imm5 PF14423 Family 12 38 171.10 29 58.91 Changed Immunity protein Imm5
Imm6 PF14434 Family 29 64 119.00 28 74.73 Changed Immunity protein Imm6
Imm7 PF15588 Family 32 42 117.50 21 78.64 New Immunity protein 7
Imm8 PF15560 Family 7 13 133.00 45 92.86 New Immunity protein 8
Imm9 PF15561 Family 5 11 140.10 38 90.75 New Immunity protein 9
ImmE5 PF11480 Family 5 26 78.30 50 81.21 Changed Colicin-E5 Imm protein
Imm_superinfect PF14373 Family 60 264 42.80 40 38.53 Changed Superinfection immunity protein
Imp-YgjV PF10688 Family 34 708 145.00 42 89.78 Changed Bacterial inner membrane protein
ImpA-rel_N PF06812 Family 143 1962 61.00 28 14.43 Changed ImpA-related N-terminal
IMPDH PF00478 Domain 84 7826 406.30 38 94.26 Changed IMP dehydrogenase / GMP reductase domain
ImpE PF07024 Family 36 372 123.30 43 45.34 Changed ImpE protein
IMP_cyclohyd PF07826 Domain 6 187 212.30 40 92.54 Changed IMP cyclohydrolase-like protein
IMS PF00817 Family 113 9024 150.20 30 34.04 Changed impB/mucB/samB family
IMS_C PF11799 Domain 106 7945 123.60 19 27.86 Changed impB/mucB/samB family C-terminal domain
IMS_HHH PF11798 Motif 92 4693 32.10 35 7.97 Changed IMS family HHH motif
InaF-motif PF15018 Motif 26 111 37.50 40 22.29 New TRP-interacting helix
IncA PF04156 Family 54 286 185.00 17 49.97 Changed IncA protein
INCA1 PF15142 Family 6 29 149.10 70 64.37 New INCA1
INCENP_ARK-bind PF03941 Family 20 272 57.30 33 6.18 Changed Inner centromere protein, ARK binding region
INCENP_N PF12178 Domain 7 80 37.40 46 4.94 Changed Chromosome passenger complex (CPC) protein INCENP N terminal
IncFII_repA PF02387 Family 22 635 239.80 41 90.66 Changed IncFII RepA protein family
Indigoidine_A PF04227 Family 90 1192 280.60 54 79.09 Changed Indigoidine synthase A like protein
ING PF12998 Domain 79 827 102.20 26 28.97 Changed Inhibitor of growth proteins N-terminal histone-binding
Inh PF02974 Domain 27 259 98.80 31 59.58 Changed Protease inhibitor Inh
Inhibitor_G39P PF11417 Family 2 43 67.20 27 43.94 Changed Loader and inhibitor of phage G40P
Inhibitor_I10 PF12559 Family 18 45 49.40 44 91.94 Changed Serine endopeptidase inhibitors
Inhibitor_I24 PF10465 Family 2 11 139.90 77 89.06 Changed PinA peptidase inhibitor
Inhibitor_I29 PF08246 Domain 95 3417 58.50 30 16.86 Changed Cathepsin propeptide inhibitor domain (I29)
Inhibitor_I34 PF10466 Family 2 7 68.40 82 97.96 Changed Saccharopepsin inhibitor I34
Inhibitor_I36 PF03995 Domain 7 93 89.90 18 54.95 Changed Peptidase inhibitor family I36
Inhibitor_I42 PF09394 Domain 103 354 92.20 23 51.54 Changed Chagasin family peptidase inhibitor I42
Inhibitor_I48 PF10467 Family 2 19 128.00 42 92.90 Changed Peptidase inhibitor clitocypin
Inhibitor_I53 PF11714 Domain 3 5 78.20 59 98.99 Changed Thrombin inhibitor Madanin
Inhibitor_I67 PF11405 Family 2 3 41.00 95 50.00 Changed Bromelain inhibitor VI
Inhibitor_I68 PF10468 Family 2 8 85.50 43 83.72 Changed Carboxypeptidase inhibitor I68
Inhibitor_I69 PF13734 Family 3 136 109.20 27 17.66 Changed Spi protease inhibitor
Inhibitor_I71 PF12628 Family 4 9 162.40 42 31.47 Changed Falstatin, cysteine peptidase inhibitor
Inhibitor_I78 PF11720 Family 8 389 62.50 29 58.57 Changed Peptidase inhibitor I78 family
Inhibitor_I9 PF05922 Domain 160 3390 81.50 20 11.78 Changed Peptidase inhibitor I9
Inhibitor_Mig-6 PF11555 Family 6 119 64.70 64 8.47 Changed EGFR receptor inhibitor Mig-6
Init_tRNA_PT PF04179 Family 20 202 381.70 35 89.56 Changed Initiator tRNA phosphoribosyl transferase
Innate_immun PF12782 Family 9 746 162.80 58 101.52 Changed Invertebrate innate immunity transcript family
Innexin PF00876 Family 99 863 283.30 22 76.49 Changed Innexin
Ino80_Iec3 PF14612 Family 22 99 161.80 30 59.05 New IEC3 subunit of the Ino80 complex, chromatin re-modelling
INO80_Ies4 PF08193 Family 11 94 211.90 32 78.21 Changed INO80 complex subunit Ies4
Inos-1-P_synth PF01658 Family 60 1141 110.30 40 26.16 Changed Myo-inositol-1-phosphate synthase
Inositol_P PF00459 Family 59 10135 256.80 24 93.87 Changed Inositol monophosphatase family
Inp1 PF12634 Family 28 115 140.90 28 25.09 Changed Inheritance of peroxisomes protein 1
Ins134_P3_kin PF05770 Family 5 297 257.30 33 79.58 Changed Inositol 1, 3, 4-trisphosphate 5/6-kinase
Ins145_P3_rec PF08709 Domain 19 714 196.90 40 6.46 Changed Inositol 1,4,5-trisphosphate/ryanodine receptor
INSIG PF07281 Family 9 298 182.60 36 62.95 Changed Insulin-induced protein (INSIG)
Insulin PF00049 Domain 28 1447 62.30 31 56.65 Changed Insulin/IGF/Relaxin family
Ins_allergen_rp PF06757 Family 38 335 174.00 23 79.51 Changed Insect allergen related repeat, nitrile-specifier detoxification
Ins_beta PF03488 Family 11 116 47.10 30 45.29 Changed Nematode insulin-related peptide beta type
Ins_P5_2-kin PF06090 Family 38 330 342.40 19 82.54 Changed Inositol-pentakisphosphate 2-kinase
Integrase_1 PF12835 Domain 21 412 159.80 31 55.67 Changed Integrase
Integrase_AP2 PF14657 Domain 212 1784 45.30 27 12.51 New AP2-like DNA-binding integrase domain
Integrase_DNA PF02920 Domain 4 459 64.40 54 14.30 Changed DNA binding domain of tn916 integrase
Integrase_Zn PF02022 Domain 92 14892 39.60 77 6.93 Changed Integrase Zinc binding domain
Integrin_alpha PF00357 Family 27 407 14.90 53 1.49 Changed Integrin alpha cytoplasmic region
Integrin_alpha2 PF08441 Family 97 1499 389.40 20 41.35 Changed Integrin alpha
Integrin_beta PF00362 Family 48 945 347.30 38 48.53 Changed Integrin, beta chain
Integrin_b_cyt PF08725 Domain 33 606 45.40 48 6.09 Changed Integrin beta cytoplasmic domain
Integrin_B_tail PF07965 Domain 58 524 83.70 32 9.93 Changed Integrin beta tail domain
Intein_splicing PF14890 Family 5 448 305.80 19 35.05 New Intein splicing domain
Interfer-bind PF09294 Domain 96 681 99.50 21 28.34 Changed Interferon-alpha/beta receptor, fibronectin type III
Interferon PF00143 Domain 15 1000 150.70 39 85.89 Changed Interferon alpha/beta domain
Internalin_N PF12354 Domain 32 845 55.90 39 10.30 Changed Bacterial adhesion/invasion protein N terminal
Intg_mem_TP0381 PF09529 Family 43 802 219.40 29 92.57 Changed Integral membrane protein (intg_mem_TP0381)
Intimin_C PF07979 Domain 14 389 94.00 48 12.60 Changed Intimin C-type lectin domain
Intron_maturas2 PF01348 Family 25 36524 102.30 63 26.36 Changed Type II intron maturase
INTS2 PF14750 Family 13 186 667.70 34 87.28 New Integrator complex subunit 2
INTS5_C PF14838 Family 6 104 471.50 28 62.76 New Integrator complex subunit 5 C-terminus
INTS5_N PF14837 Family 17 78 214.30 46 23.26 New Integrator complex subunit 5 N-terminus
INT_SG_DDX_CT_C PF15300 Family 36 206 64.00 48 9.46 New INTS6/SAGE1/DDX26B/CT45 C-terminus
Invasin_D3 PF09134 Domain 2 269 102.50 72 8.12 Changed Invasin, domain 3
Invas_SpaK PF03519 Family 7 181 77.60 50 58.83 Changed Invasion protein B family
InvH PF04741 Family 3 211 116.60 64 95.63 Changed InvH outer membrane lipoprotein
Involucrin PF00904 Repeat 129 691 10.00 64 70.08 Changed Involucrin repeat
Involucrin2 PF06994 Family 38 508 41.10 53 104.60 Changed Involucrin
Involucrin_N PF10583 Domain 9 42 68.00 69 15.11 Changed Involucrin of squamous epithelia N-terminus
IN_DBD_C PF00552 Domain 37 14492 49.90 85 8.72 Changed Integrase DNA binding domain
Ion_trans PF00520 Family 285 20399 196.60 17 31.06 Changed Ion transport protein
Ion_trans_2 PF07885 Domain 123 9163 81.40 21 22.30 Changed Ion channel
Ion_trans_N PF08412 Family 9 383 66.70 47 8.90 Changed Ion transport protein N-terminal
IpaB_EvcA PF03278 Family 9 303 135.40 47 82.57 Changed IpaB/EvcA family
IpaC_SipC PF09599 Family 5 167 338.40 53 86.65 Changed Salmonella-Shigella invasin protein C (IpaC_SipC)
IpaD PF06511 Family 3 264 261.50 40 88.15 Changed Invasion plasmid antigen IpaD
IpgD PF05925 Family 2 189 503.80 70 94.95 Changed Enterobacterial virulence protein IpgD
iPGM_N PF06415 Domain 35 2910 216.40 43 44.36 Changed BPG-independent PGAM N-terminus (iPGM_N)
Ipi1_N PF12333 Family 43 316 102.20 27 18.54 Changed Rix1 complex component involved in 60S ribosome maturation
IPI_T4 PF11634 Family 2 6 75.70 85 79.37 Changed Nuclease inhibitor from bacteriophage T4
IPK PF03770 Family 109 1104 210.70 27 40.30 Changed Inositol polyphosphate kinase
IPP-2 PF04979 Family 20 478 115.20 26 55.30 Changed Protein phosphatase inhibitor 2 (IPP-2)
IPPT PF01715 Family 12 5290 236.80 32 78.09 Changed IPP transferase
IPT PF01745 Family 7 88 163.70 35 80.48 Changed Isopentenyl transferase
IP_trans PF02121 Family 4 692 221.10 45 46.39 Changed Phosphatidylinositol transfer protein
IQ PF00612 Motif 345 16654 20.70 32 5.40 Changed IQ calmodulin-binding motif
IQ-like PF15157 Family 3 41 89.20 78 58.91 New IQ-like
IR1-M PF12185 Domain 4 96 62.00 51 4.32 Changed Nup358/RanBP2 E3 ligase domain
IRF PF00605 Domain 26 872 105.30 43 28.65 Changed Interferon regulatory factor transcription factor
IRF-2BP1_2 PF11261 Domain 11 146 53.40 76 10.11 Changed Interferon regulatory factor 2-binding protein zinc finger
IRF-3 PF10401 Family 43 649 168.80 31 40.48 Changed Interferon-regulatory factor 3
IRK PF01007 Family 13 1452 284.90 37 78.63 Changed Inward rectifier potassium channel
IRK_N PF08466 Family 5 111 45.20 67 10.61 Changed Inward rectifier potassium channel N-terminal
Iron_permease PF04120 Family 19 374 117.30 31 64.84 Changed Low affinity iron permease
Iron_traffic PF04362 Family 65 1349 87.20 59 96.06 Changed Bacterial Fe(2+) trafficking
Iron_transport PF10634 Family 30 560 153.60 53 80.44 Changed Fe2+ transport protein
IRS PF02174 Domain 32 923 96.60 28 10.89 Changed PTB domain (IRS-1 type)
ISAV_HA PF06215 Family 3 464 318.40 88 99.80 Changed Infectious salmon anaemia virus haemagglutinin
ISG65-75 PF11727 Family 20 223 254.70 29 57.37 Changed Invariant surface glycoprotein
Ish1 PF10281 Repeat 71 642 37.40 36 30.74 Changed Putative stress-responsive nuclear envelope protein
ISK_Channel PF02060 Family 3 180 96.40 30 75.87 Changed Slow voltage-gated potassium channel
ISN1 PF06437 Family 18 157 373.80 47 89.08 Changed IMP-specific 5'-nucleotidase
Isochorismatase PF00857 Family 64 13319 172.10 20 81.06 Changed Isochorismatase family
Iso_dh PF00180 Domain 23 12354 320.30 29 93.82 Changed Isocitrate/isopropylmalate dehydrogenase
IspA PF04279 Family 129 1696 176.80 39 93.65 Changed Intracellular septation protein A
IspD PF01128 Family 6 4492 220.50 32 84.34 Changed 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
Ist1 PF03398 Family 44 593 152.10 33 39.47 Changed Regulator of Vps4 activity in the MVB pathway
IstB_IS21 PF01695 Family 17 7213 156.90 22 63.86 Changed IstB-like ATP binding protein
IstB_IS21_ATP PF08483 Family 15 366 30.00 42 12.31 Changed IstB-like ATP binding N-terminal
Isy1 PF06246 Family 31 342 234.50 38 85.85 Changed Isy1-like splicing family
ITAM PF02189 Motif 12 339 21.10 35 14.82 Changed Immunoreceptor tyrosine-based activation motif
ITAM_Cys-rich PF10538 Domain 6 300 24.00 71 2.81 Changed Immunoreceptor tyrosine-based activation motif
ITI_HC_C PF06668 Family 29 404 177.50 33 20.30 Changed Inter-alpha-trypsin inhibitor heavy chain C-terminus
IucA_IucC PF04183 Family 168 2438 241.30 25 40.66 Changed IucA / IucC family
IU_nuc_hydro PF01156 Domain 118 5444 302.10 28 95.00 Changed Inosine-uridine preferring nucleoside hydrolase
Ivy PF08816 Family 17 506 116.00 56 74.15 Changed Inhibitor of vertebrate lysozyme (Ivy)
IZUMO PF15005 Family 8 129 145.10 28 60.57 New Izumo sperm-egg fusion
I_LWEQ PF01608 Family 22 586 147.60 43 10.97 Changed I/LWEQ domain
New Top twenty Numbers A B C D E F G H I J K L M N O P Q R S T U V W X Y Z