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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: A5YV76_PIG (A5YV76)

Summary

This is the summary of UniProt entry A5YV76_PIG (A5YV76).

Description: Fatty acid synthase
Source organism: Sus scrofa (Pig) (NCBI taxonomy ID 9823)
View Pfam proteome data.
Length: 2512 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A ketoacyl-synt 1 239
low_complexity n/a 102 114
low_complexity n/a 160 174
Pfam A Ketoacyl-synt_C 243 360
disorder n/a 255 264
disorder n/a 274 275
disorder n/a 287 296
disorder n/a 300 301
disorder n/a 322 329
disorder n/a 332 333
disorder n/a 359 362
disorder n/a 364 365
disorder n/a 368 371
disorder n/a 404 422
low_complexity n/a 409 426
Pfam A Acyl_transf_1 493 810
Pfam A PS-DH 857 1091
disorder n/a 1165 1168
disorder n/a 1170 1174
low_complexity n/a 1183 1204
low_complexity n/a 1210 1222
Pfam A Methyltransf_12 1245 1344
disorder n/a 1272 1275
low_complexity n/a 1280 1292
disorder n/a 1285 1287
disorder n/a 1295 1297
disorder n/a 1299 1303
low_complexity n/a 1338 1356
disorder n/a 1484 1485
disorder n/a 1488 1490
Pfam A ADH_zinc_N 1679 1816
disorder n/a 1867 1868
Pfam A KR 1886 2066
low_complexity n/a 1891 1900
disorder n/a 2122 2123
Pfam A PP-binding 2126 2192
disorder n/a 2191 2213
Pfam A Thioesterase 2243 2502
low_complexity n/a 2485 2498

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession A5YV76. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEEVVIAGMS GKLPESENLE EFWANLIGGV DMVTADDRRW KAGLYGLPRR
50
51
MGKLKDLSRF DASFFGVHSK QANTMDPQLR MLLEVTYEAI VDGGINPASL
100
101
RGTSTGVWVG VSSSDASEAL SRDPETLVGY SMIGCQRAMM ANRLSFFFDF
150
151
KGPSITIDTA CSSSLLALQS AYQAIRGGEC SAAVVGGLNV LLKPNSSLQF
200
201
MKLGMLSQDG TCRSFDAEGT GYCRAEAVVA VLLTKKSLAR RVYATILNAG
250
251
TNTDGSKEQG VTFPSGDVQE QLIRSLYAPA GPDPESLEYI EAHGTGTKVG
300
301
DPQELNGIVN ALCATRREPL LIGSTKSNMG HPEPASGVAA LIKVLLSLEH
350
351
GVWAPNLHYH TPNPEIPALQ DGRLQVVDRP LPIRGGNVGI NSFGFGGSNV
400
401
HVILQPNSRP APPPAQHAAL PRLLQASGRT LEAVQTLLEQ GLRHSRDLAF
450
451
VGMLNEIAAV SPVAMPFRGY AVLGGEAGSQ EVQQVPGSKR PVWFICSGMG
500
501
AQWQGMGLSL MRLDRFRDSI LRSDQALKPL GLRVSDLLLS TDEAVLDDIV
550
551
SSFVSLTSIQ IALIDLLTSL GLQPDGIIGH SLGEVACGYA DGCLTQEEAV
600
601
LSSYWRGYCI KEANVLPGAM AAVGLSWEEC KQRCPPGIVP ACHNSKDTVT
650
651
ISGPQAAMSE FLQQLKREDV FVKEVRTGGI AFHSYFMESI APTLLRQLRK
700
701
VILDPKPRSK RWLSTSIPEA QWQGSLARTF SAEYSVNNLV SPVLFQEALQ
750
751
HVPAHAVVVE IAPHALLQAV LKRSLESSCT IIPLMKKDHR DNLEFFLSNV
800
801
GRLHLAGVSV NPNGLFPPVE FPAPRGTPLI SPHXKWDHSQ AWDVPSAADF
850
851
PSGSSCSSVA VYKFDVSPES PDHYLVDHCI DGRVLFPGTG YLWLTWKTLA
900
901
RALSQNLEET PVVFEDVTLH QATILPKTGT VSLEVRLLEA SHAFEVSDSN
950
951
GSLIASGKVY QWESPDPKLF DTRAAVDPAD STAEFRLSQG DVYKDLRLRG
1000
1001
YDYGPFFQLV LESDLEGNRG RLQWNDSWVS FLDAMLHMSI LAPGQLGLYL
1050
1051
PTRFTSIRID PVTHRQKLYT LQDTTQAADV VVDRNLNTVV AGGALFLGAH
1100
1101
SSVAPRRPQE HLKPILEKFC FTPHVESGCL AGNTALQEEL QLCRGLAQAL
1150
1151
QTKVAQQGLK MVVPGLDGAQ APREAPQQSL PRLLAAACQL QLNGNLQLEL
1200
1201
GQVLAQERPL LCDDPLLSGL LDAPALKACV DTALENMASP KMKVVEVLAG
1250
1251
DGQLYSRIPA LLNTQPVMDL DYTATDRNPQ ALEAAQAKLE QLHVTQGQWD
1300
1301
PANPAPGSLG KADLLVCNCA LATLGDPAVA VGNMAATLKE GGFLLLHTLL
1350
1351
AGHPLGEMVG FLTSPEQGGR HLLSQDQWES LFAGASLHLV ALKRSFYGSV
1400
1401
LFLCRQQTPQ DSPVFLSVED TSFRWVDSLK DILADASSRP VWLMAVGCST
1450
1451
SGVVGMVNCL RKEPGGHRIR CVLVSNLSST SPAPEMHPSS SELQKVLQGD
1500
1501
LVMNVYRDGA WGAFRHFPLE QDRPEKQTEH AFVNVLSRGD LSSIRWVCSP
1550
1551
LHYALPASCQ DRLCSVYYTS LNFRDVMLAT GKLSPDSIPG KWLTRDCMLG
1600
1601
MEFSGRDASG RRVMGMVPAE GLATSVLLLQ HATWEVPSTW TLEEAASVPI
1650
1651
VYTTAYYSLV VRGRMQPGES VLIHSGSGGV GQAAIAIALS RGCRVFTTVG
1700
1701
SAEKRAYLQA RFPQLDETCF ANSRDTSFEQ HVLRHTAGKG VDLVLNSLAE
1750
1751
EKLQASVRCL AQHGRFLEIG KFDLSNNHAL GMAVFLKNVT FHGILLDSLF
1800
1801
EEGGATWQEV SELLKAGIQE GVVQPLKCTV FPRTKVEAAF RYMAQGKHIG
1850
1851
KVVIQVREEE QGPAPRGLPP IALTGLSKTF CPPHKSYVIT GGLGGFGLQL
1900
1901
AQWLRLRGAQ KLVLTSRSGI RTGYQARQVR EWRRQGVQVL VSTSNASSLD
1950
1951
GARSLITEAT QLGPVGGVFN LAMVLRDAVL ENQTPEFFQD VSKPKYSGTA
2000
2001
NLDRVTREAC PELDYFVIFS SVSCGRGNAG QANYGFANSA MERICEKRRH
2050
2051
DGLPGLAVQW GAIGDVGVVL ETMGTNDTVI GGTLPQRIAS CLEVLDLFLS
2100
2101
QPHPVLSSFV LAEKKAAAPR DGSSQKDLVK AVAHILGIRD VASINPDSTL
2150
2151
VDLGLDSLMG VEVRQILERE HDLVLSMREV RQLSLRKLQE LSSKTSTDAD
2200
2201
PATPTSHEDS PVRQQATLNL STLLVNPEGP TLTRLNSVQS AERPLFLVHP
2250
2251
IEGSITVFHG LAAKLSIPTY GLQCTGAAPL DSIQSLASYY IECIRQVQPE
2300
2301
GPYRIAGYSY GACVAFEMCS QLQAQQSATP GNHSLFLFDG SHTFVLAYTQ
2350
2351
SVRAKMTPGC EAEAEAKAMY FFVQQFTDME QGKVLEALIP LQGLEARVAA
2400
2401
TVDLITQSHA GLDRHALSFA ARSFYQKLRA AENYWPQATY HGNVTLLRAK
2450
2451
TGGAYGEDLG ADYNLSQVCD GKVSVHVIEG DHRTLLEGSG LESILSIIHS
2500
2501
CLAEPRVSVR EG                                         
2512
 

Show the unformatted sequence.

Checksums:
CRC64:F57ABBAAC73E4B19
MD5:bf42b8b4e84e2b5d2624ad22e1f30f02

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Acyl_transf_1 493 - 810 2VZ8 A 493 - 810 Jmol AstexViewer SPICE
B 493 - 810 Jmol AstexViewer SPICE
2VZ9 A 493 - 810 Jmol AstexViewer SPICE
B 493 - 810 Jmol AstexViewer SPICE
ADH_zinc_N 1679 - 1816 2VZ8 A 1679 - 1816 Jmol AstexViewer SPICE
B 1679 - 1816 Jmol AstexViewer SPICE
2VZ9 A 1679 - 1816 Jmol AstexViewer SPICE
B 1679 - 1816 Jmol AstexViewer SPICE
ketoacyl-synt 1 - 239 2VZ8 A 1 - 239 Jmol AstexViewer SPICE
B 1 - 239 Jmol AstexViewer SPICE
2VZ9 A 1 - 239 Jmol AstexViewer SPICE
B 1 - 239 Jmol AstexViewer SPICE
Ketoacyl-synt_C 243 - 360 2VZ8 A 243 - 360 Jmol AstexViewer SPICE
B 243 - 360 Jmol AstexViewer SPICE
2VZ9 A 243 - 360 Jmol AstexViewer SPICE
B 243 - 360 Jmol AstexViewer SPICE
KR 1886 - 2066 2VZ8 A 1886 - 2066 Jmol AstexViewer SPICE
B 1886 - 2066 Jmol AstexViewer SPICE
2VZ9 A 1886 - 2066 Jmol AstexViewer SPICE
B 1886 - 2066 Jmol AstexViewer SPICE
Methyltransf_12 1245 - 1344 2VZ8 A 1245 - 1344 Jmol AstexViewer SPICE
B 1245 - 1344 Jmol AstexViewer SPICE
2VZ9 A 1245 - 1344 Jmol AstexViewer SPICE
B 1245 - 1344 Jmol AstexViewer SPICE
PS-DH 857 - 1091 2VZ8 A 857 - 1091 Jmol AstexViewer SPICE
B 857 - 1091 Jmol AstexViewer SPICE
2VZ9 A 857 - 1091 Jmol AstexViewer SPICE
B 857 - 1091 Jmol AstexViewer SPICE