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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: E5KIY2_ECOLX (E5KIY2)

Summary

This is the summary of UniProt entry E5KIY2_ECOLX (E5KIY2).

Description: New Delhi metallo-beta-lactamase-1
Source organism: Escherichia coli (NCBI taxonomy ID 562)
Length: 270 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 28
low_complexity n/a 11 23
disorder n/a 33 38
Pfam A Lactamase_B 70 250
low_complexity n/a 230 244
disorder n/a 259 261

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession E5KIY2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MELPNIMHPV AKLSTALAAA LMLSGCMPGE IRPTIGQQME TGDQRFGDLV
50
51
FRQLAPNVWQ HTSYLDMPGF GAVASNGLIV RDGGRVLVVD TAWTDDQTAQ
100
101
ILNWIKQEIN LPVALAVVTH AHQDKMGGMD ALHAAGIATY ANALSNQLAP
150
151
QEGMVAAQHS LTFAANGWVE PATAPNFGPL KVFYPGPGHT SDNITVGIDG
200
201
TDIAFGGCLI KDSKAKSLGN LGDADTEHYA ASARAFGAAF PKASMIVMSH
250
251
SAPDSRAAIT HTARMADKLR                                 
270
 

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Checksums:
CRC64:1B6009120B945F14
MD5:285ed34de1e34401121b61c709f5992d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Lactamase_B 70 - 250 3S0Z A 70 - 250 Jmol AstexViewer SPICE
B 70 - 250 Jmol AstexViewer SPICE