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11  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CLIC1_HUMAN (O00299)

Summary

This is the summary of UniProt entry CLIC1_HUMAN (O00299).

Description: Chloride intracellular channel protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 241 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A GST_N_2 23 87
Pfam A GST_C_2 122 212
disorder n/a 149 161

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O00299. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEEQPQVEL FVKAGSDGAK IGNCPFSQRL FMVLWLKGVT FNVTTVDTKR
50
51
RTETVQKLCP GGQLPFLLYG TEVHTDTNKI EEFLEAVLCP PRYPKLAALN
100
101
PESNTAGLDI FAKFSAYIKN SNPALNDNLE KGLLKALKVL DNYLTSPLPE
150
151
EVDETSAEDE GVSQRKFLDG NELTLADCNL LPKLHIVQVV CKKYRGFTIP
200
201
EAFRGVHRYL SNAYAREEFA STCPDDEEIE LAYEQVAKAL K         
241
 

Show the unformatted sequence.

Checksums:
CRC64:163EEB7481826A0A
MD5:cacfbd0a5eaea5afb46b2e4796e1f1c9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
GST_C_2 122 - 212 1K0M A 122 - 212 Jmol AstexViewer SPICE
B 122 - 212 Jmol AstexViewer SPICE
1K0N A 122 - 212 Jmol AstexViewer SPICE
B 122 - 212 Jmol AstexViewer SPICE
1K0O A 122 - 212 Jmol AstexViewer SPICE
B 122 - 212 Jmol AstexViewer SPICE
1RK4 A 122 - 212 Jmol AstexViewer SPICE
B 122 - 212 Jmol AstexViewer SPICE
3O3T A 122 - 212 Jmol AstexViewer SPICE
3P8W A 122 - 212 Jmol AstexViewer SPICE
3P90 A 122 - 212 Jmol AstexViewer SPICE
3QR6 A 122 - 212 Jmol AstexViewer SPICE
3SWL A 122 - 212 Jmol AstexViewer SPICE
3TGZ A 122 - 212 Jmol AstexViewer SPICE
B 122 - 212 Jmol AstexViewer SPICE
3UVH A 122 - 212 Jmol AstexViewer SPICE
B 122 - 212 Jmol AstexViewer SPICE
GST_N_2 23 - 87 1K0M A 23 - 87 Jmol AstexViewer SPICE
B 23 - 87 Jmol AstexViewer SPICE
1K0N A 23 - 87 Jmol AstexViewer SPICE
B 23 - 87 Jmol AstexViewer SPICE
1K0O A 23 - 87 Jmol AstexViewer SPICE
B 23 - 87 Jmol AstexViewer SPICE
1RK4 A 23 - 87 Jmol AstexViewer SPICE
B 23 - 87 Jmol AstexViewer SPICE
3O3T A 23 - 87 Jmol AstexViewer SPICE
3P8W A 23 - 87 Jmol AstexViewer SPICE
3P90 A 23 - 87 Jmol AstexViewer SPICE
3QR6 A 23 - 87 Jmol AstexViewer SPICE
3SWL A 23 - 87 Jmol AstexViewer SPICE
3TGZ A 23 - 87 Jmol AstexViewer SPICE
B 23 - 87 Jmol AstexViewer SPICE
3UVH A 23 - 87 Jmol AstexViewer SPICE
B 23 - 87 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.