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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PKND_MYCTU (O05871)

Summary

This is the summary of UniProt entry PKND_MYCTU (O05871).

Description: Serine/threonine-protein kinase pknD EC=2.7.11.1
Source organism: Mycobacterium tuberculosis (NCBI taxonomy ID 1773)
View Pfam proteome data.
Length: 664 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Pkinase 15 271
low_complexity n/a 17 27
low_complexity n/a 113 125
disorder n/a 227 250
disorder n/a 273 276
disorder n/a 279 293
disorder n/a 295 368
low_complexity n/a 313 325
transmembrane n/a 379 402
low_complexity n/a 381 401
Pfam A NHL 426 453
Pfam A NHL 468 493
Pfam A NHL 509 536
Pfam A NHL 551 578
disorder n/a 559 564
disorder n/a 573 574
Pfam A NHL 594 620
Pfam A NHL 635 662

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O05871. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSDAVPQVGS QFGPYQLLRL LGRGGMGEVY EAEDTRKHRV VALKLISPQY
50
51
SDNAVFRARM QREADTAGRL TEPHIVPIHD YGEINGQFFV EMRMIDGTSL
100
101
RALLKQYGPL TPARAVAIVR QIAAALDAAH ANGVTHRDVK PENILVTASD
150
151
FAYLVDFGIA RAASDPGLTQ TGTAVGTYNY MAPERFTGDE VTYRADIYAL
200
201
ACVLGECLTG APPYRADSVE RLIAAHLMDP APQPSQLRPG RVPPALDQVI
250
251
AKGMAKNPAE RFMSAGDLAI AAHDALTTSE QHQATTILRR GDNATLLATP
300
301
ADTGLSQSES GIAGAGTGPP TPGAARWSPG DSATVAGPLA ADSRGGNWPS
350
351
QTGHSPAVPN ALQASLGHAV PPAGNKRKVW AVVGAAAIVL VAIVAAAGYL
400
401
VLRPSWSPTQ ASGQTVLPFT GIDFRLSPSG VAVDSAGNVY VTSEGMYGRV
450
451
VKLATGSTGT TVLPFNGLYQ PQGLAVDGAG TVYVTDFNNR VVTLAAGSNN
500
501
QTVLPFDGLN YPEGLAVDTQ GAVYVADRGN NRVVKLAAGS KTQTVLPFTG
550
551
LNDPDGVAVD NSGNVYVTDT DNNRVVKLEA ESNNQVVLPF TDITAPWGIA
600
601
VDEAGTVYVT EHNTNQVVKL LAGSTTSTVL PFTGLNTPLA VAVDSDRTVY
650
651
VADRGNDRVV KLTS                                       
664
 

Show the unformatted sequence.

Checksums:
CRC64:FE39716825A41CC1
MD5:1249486d3f93821750f8224457ac079f

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
NHL 426 - 453 1RWI A 24 - 51 Jmol AstexViewer SPICE
B 24 - 51 Jmol AstexViewer SPICE
1RWL A 24 - 51 Jmol AstexViewer SPICE
468 - 493 1RWI A 66 - 91 Jmol AstexViewer SPICE
B 66 - 91 Jmol AstexViewer SPICE
1RWL A 66 - 91 Jmol AstexViewer SPICE
509 - 536 1RWI A 107 - 134 Jmol AstexViewer SPICE
B 107 - 134 Jmol AstexViewer SPICE
1RWL A 107 - 134 Jmol AstexViewer SPICE
551 - 578 1RWI A 149 - 176 Jmol AstexViewer SPICE
B 149 - 176 Jmol AstexViewer SPICE
1RWL A 149 - 176 Jmol AstexViewer SPICE
594 - 620 1RWI A 192 - 218 Jmol AstexViewer SPICE
B 192 - 218 Jmol AstexViewer SPICE
1RWL A 192 - 218 Jmol AstexViewer SPICE
635 - 662 1RWI A 233 - 260 Jmol AstexViewer SPICE
B 233 - 260 Jmol AstexViewer SPICE
1RWL A 233 - 260 Jmol AstexViewer SPICE