Summary
This is the summary of UniProt entry PKND_MYCTU (O05871).
| Description: | Serine/threonine-protein kinase pknD EC=2.7.11.1 |
| Source organism: |
Mycobacterium tuberculosis
(NCBI taxonomy ID
1773)
View Pfam proteome data. |
| Length: | 664 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | Pkinase | 15 | 271 |
| low_complexity | n/a | 17 | 27 |
| low_complexity | n/a | 113 | 125 |
| disorder | n/a | 227 | 250 |
| disorder | n/a | 273 | 276 |
| disorder | n/a | 279 | 293 |
| disorder | n/a | 295 | 368 |
| low_complexity | n/a | 313 | 325 |
| transmembrane | n/a | 379 | 402 |
| low_complexity | n/a | 381 | 401 |
| Pfam A | NHL | 426 | 453 |
| Pfam A | NHL | 468 | 493 |
| Pfam A | NHL | 509 | 536 |
| Pfam A | NHL | 551 | 578 |
| disorder | n/a | 559 | 564 |
| disorder | n/a | 573 | 574 |
| Pfam A | NHL | 594 | 620 |
| Pfam A | NHL | 635 | 662 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O05871. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSDAVPQVGS QFGPYQLLRL LGRGGMGEVY EAEDTRKHRV VALKLISPQY
50 51
SDNAVFRARM QREADTAGRL TEPHIVPIHD YGEINGQFFV EMRMIDGTSL
100 101
RALLKQYGPL TPARAVAIVR QIAAALDAAH ANGVTHRDVK PENILVTASD
150 151
FAYLVDFGIA RAASDPGLTQ TGTAVGTYNY MAPERFTGDE VTYRADIYAL
200 201
ACVLGECLTG APPYRADSVE RLIAAHLMDP APQPSQLRPG RVPPALDQVI
250 251
AKGMAKNPAE RFMSAGDLAI AAHDALTTSE QHQATTILRR GDNATLLATP
300 301
ADTGLSQSES GIAGAGTGPP TPGAARWSPG DSATVAGPLA ADSRGGNWPS
350 351
QTGHSPAVPN ALQASLGHAV PPAGNKRKVW AVVGAAAIVL VAIVAAAGYL
400 401
VLRPSWSPTQ ASGQTVLPFT GIDFRLSPSG VAVDSAGNVY VTSEGMYGRV
450 451
VKLATGSTGT TVLPFNGLYQ PQGLAVDGAG TVYVTDFNNR VVTLAAGSNN
500 501
QTVLPFDGLN YPEGLAVDTQ GAVYVADRGN NRVVKLAAGS KTQTVLPFTG
550 551
LNDPDGVAVD NSGNVYVTDT DNNRVVKLEA ESNNQVVLPF TDITAPWGIA
600 601
VDEAGTVYVT EHNTNQVVKL LAGSTTSTVL PFTGLNTPLA VAVDSDRTVY
650 651
VADRGNDRVV KLTS
664
Show the unformatted sequence. |
| Checksums: |
CRC64:FE39716825A41CC1
MD5:1249486d3f93821750f8224457ac079f
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| NHL | 426 - 453 | 1RWI | A | 24 - 51 | Jmol AstexViewer SPICE |
| B | 24 - 51 | Jmol AstexViewer SPICE | |||
| 1RWL | A | 24 - 51 | Jmol AstexViewer SPICE | ||
| 468 - 493 | 1RWI | A | 66 - 91 | Jmol AstexViewer SPICE | |
| B | 66 - 91 | Jmol AstexViewer SPICE | |||
| 1RWL | A | 66 - 91 | Jmol AstexViewer SPICE | ||
| 509 - 536 | 1RWI | A | 107 - 134 | Jmol AstexViewer SPICE | |
| B | 107 - 134 | Jmol AstexViewer SPICE | |||
| 1RWL | A | 107 - 134 | Jmol AstexViewer SPICE | ||
| 551 - 578 | 1RWI | A | 149 - 176 | Jmol AstexViewer SPICE | |
| B | 149 - 176 | Jmol AstexViewer SPICE | |||
| 1RWL | A | 149 - 176 | Jmol AstexViewer SPICE | ||
| 594 - 620 | 1RWI | A | 192 - 218 | Jmol AstexViewer SPICE | |
| B | 192 - 218 | Jmol AstexViewer SPICE | |||
| 1RWL | A | 192 - 218 | Jmol AstexViewer SPICE | ||
| 635 - 662 | 1RWI | A | 233 - 260 | Jmol AstexViewer SPICE | |
| B | 233 - 260 | Jmol AstexViewer SPICE | |||
| 1RWL | A | 233 - 260 | Jmol AstexViewer SPICE |