Summary
This is the summary of UniProt entry ADCY6_HUMAN (O43306).
| Description: | Adenylate cyclase type 6 EC=4.6.1.1 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1168 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_35838 | 1 | 49 |
| disorder | n/a | 14 | 34 |
| disorder | n/a | 49 | 70 |
| low_complexity | n/a | 52 | 64 |
| low_complexity | n/a | 94 | 107 |
| disorder | n/a | 101 | 107 |
| Pfam B | Pfam-B_3590 | 122 | 239 |
| transmembrane | n/a | 152 | 172 |
| low_complexity | n/a | 152 | 168 |
| transmembrane | n/a | 178 | 198 |
| low_complexity | n/a | 182 | 190 |
| transmembrane | n/a | 210 | 230 |
| low_complexity | n/a | 214 | 230 |
| transmembrane | n/a | 236 | 253 |
| transmembrane | n/a | 260 | 278 |
| transmembrane | n/a | 290 | 310 |
| Pfam A | Guanylate_cyc | 370 | 554 |
| disorder | n/a | 537 | 538 |
| disorder | n/a | 564 | 568 |
| Pfam A | DUF1053 | 578 | 669 |
| disorder | n/a | 601 | 606 |
| disorder | n/a | 609 | 616 |
| transmembrane | n/a | 669 | 690 |
| low_complexity | n/a | 677 | 691 |
| transmembrane | n/a | 696 | 721 |
| transmembrane | n/a | 742 | 762 |
| transmembrane | n/a | 815 | 833 |
| transmembrane | n/a | 840 | 862 |
| low_complexity | n/a | 844 | 856 |
| transmembrane | n/a | 893 | 911 |
| Pfam A | Guanylate_cyc | 970 | 1164 |
| disorder | n/a | 1118 | 1120 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O43306. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSWFSGLLVP KVDERKTAWG ERNGQKRSRR RGTRAGGFCT PRYMSCLRDA
50 51
EPPSPTPAGP PRCPWQDDAF IRRGGPGKGK ELGLRAVALG FEDTEVTTTA
100 101
GGTAEVAPDA VPRSGRSCWR RLVQVFQSKQ FRSAKLERLY QRYFFQMNQS
150 151
SLTLLMAVLV LLTAVLLAFH AAPARPQPAY VALLACAAAL FVGLMVVCNR
200 201
HSFRQDSMWV VSYVVLGILA AVQVGGALAA DPRSPSAGLW CPVFFVYIAY
250 251
TLLPIRMRAA VLSGLGLSTL HLILAWQLNR GDAFLWKQLG ANVLLFLCTN
300 301
VIGICTHYPA EVSQRQAFQE TRGYIQARLH LQHENRQQER LLLSVLPQHV
350 351
AMEMKEDINT KKEDMMFHKI YIQKHDNVSI LFADIEGFTS LASQCTAQEL
400 401
VMTLNELFAR FDKLAAENHC LRIKILGDCY YCVSGLPEAR ADHAHCCVEM
450 451
GVDMIEAISL VREVTGVNVN MRVGIHSGRV HCGVLGLRKW QFDVWSNDVT
500 501
LANHMEAGGR AGRIHITRAT LQYLNGDYEV EPGRGGERNA YLKEQHIETF
550 551
LILGASQKRK EEKAMLAKLQ RTRANSMEGL MPRWVPDRAF SRTKDSKAFR
600 601
QMGIDDSSKD NRGTQDALNP EDEVDEFLSR AIDARSIDQL RKDHVRRFLL
650 651
TFQREDLEKK YSRKVDPRFG AYVACALLVF CFICFIQLLI FPHSTLMLGI
700 701
YASIFLLLLI TVLICAVYSC GSLFPKALQR LSRSIVRSRA HSTAVGIFSV
750 751
LLVFTSAIAN MFTCNHTPIR SCAARMLNLT PADITACHLQ QLNYSLGLDA
800 801
PLCEGTMPTC SFPEYFIGNM LLSLLASSVF LHISSIGKLA MIFVLGLIYL
850 851
VLLLLGPPAT IFDNYDLLLG VHGLASSNET FDGLDCPAAG RVALKYMTPV
900 901
ILLVFALALY LHAQQVESTA RLDFLWKLQA TGEKEEMEEL QAYNRRLLHN
950 951
ILPKDVAAHF LARERRNDEL YYQSCECVAV MFASIANFSE FYVELEANNE
1000 1001
GVECLRLLNE IIADFDEIIS EERFRQLEKI KTIGSTYMAA SGLNASTYDQ
1050 1051
VGRSHITALA DYAMRLMEQM KHINEHSFNN FQMKIGLNMG PVVAGVIGAR
1100 1101
KPQYDIWGNT VNVSSRMDST GVPDRIQVTT DLYQVLAAKG YQLECRGVVK
1150 1151
VKGKGEMTTY FLNGGPSS
1168
Show the unformatted sequence. |
| Checksums: |
CRC64:127BB6E67F73AA61
MD5:409f13cff38ea1bfae700e133e5a939c
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.