Summary
This is the summary of UniProt entry O44049_TRYRA (O44049).
| Description: | Sialidase EC=3.2.1.18 |
| Source organism: |
Trypanosoma rangeli
(NCBI taxonomy ID
5698)
|
| Length: | 660 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 22 |
| disorder | n/a | 143 | 144 |
| Pfam B | Pfam-B_356658 | 245 | 297 |
| Pfam A | Laminin_G_3 | 474 | 641 |
| disorder | n/a | 656 | 657 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O44049. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MSWLAVFVPL FLMACASEPA SALAPGSSRV ELFKRKNSTV PFEESNGTIR
50 51
ERVVHSFRIP TIVNVDGVMV ATADARYETS FDNSFIETAV KYSVDDGATW
100 101
NTQIAIKNSR ASSVSRVMDA TVIVKGNKLY ILVGSFNKTR NSWTQHRDGS
150 151
DWEPLLVVGE VTKSAANGKT TATISWGKPV SLKPLFPAEF DGILTKEFIG
200 201
GVGAAIVGSN GNLVYPVQIA DMGGRVFTKI MYSEDDGNTW KFAEGRSKFG
250 251
CSEPAVLEWE GKLIINNRVD GNRRLVYESS DMGKTWVEAL GTLSHVWTNS
300 301
PTSNQQDCQS SFVAVTIEGK RVMLFTHPLN LKGRWMRDRL HLWMTDNQRI
350 351
FDVGQISIGD ENSGYSSVLY KDDKLYSLHE INTNDVYSLV FVRFIGELQL
400 401
MKSVVRTWKE EDNHLASICT PVVPATPPSK GGCGAAVPTA GLVGFLSHSA
450 451
NGSVWEDVYR CVDANVANAE RVPNGLKFNG VGGGAVWPVA RQGQTRRYQF
500 501
ANYRFTLVAT VTIDELPKGT SPLLGAGLEG PGDAKLLGLS YDKNRQWRPL
550 551
YGAAPASPTG SWELHKKYHV VLTMADRQGS VYVDGQPLAG SGNTVVRGAT
600 601
LPDISHFYIG GPRSKGAPTD SRVTVTNIVL YNRRLNSSEI RTLFLSQDMI
650 651
GTDGGAGTAA
660
Show the unformatted sequence. |
| Checksums: |
CRC64:B5D55765DC4423D0
MD5:6b7f6a33a2125565576ce602d4d5b9b3
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| Laminin_G_3 | 474 - 641 | 1MZ5 | A | 452 - 619 | Jmol AstexViewer SPICE |
| 1MZ6 | A | 452 - 619 | Jmol AstexViewer SPICE | ||
| 1N1S | A | 455 - 622 | Jmol AstexViewer SPICE | ||
| 1N1T | A | 455 - 622 | Jmol AstexViewer SPICE | ||
| 1N1V | A | 455 - 622 | Jmol AstexViewer SPICE | ||
| 1N1Y | A | 455 - 622 | Jmol AstexViewer SPICE | ||
| 1WCS | A | 455 - 622 | Jmol AstexViewer SPICE | ||
| 2A75 | A | 452 - 619 | Jmol AstexViewer SPICE | ||
| 2AGS | A | 452 - 619 | Jmol AstexViewer SPICE | ||
| 2FHR | A | 452 - 619 | Jmol AstexViewer SPICE |