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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CC14B_HUMAN (O60729)

Summary

This is the summary of UniProt entry CC14B_HUMAN (O60729).

Description: Dual specificity protein phosphatase CDC14B EC=3.1.3.16 EC=3.1.3.48
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 498 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
low_complexity n/a 15 26
disorder n/a 28 45
low_complexity n/a 36 47
Pfam A DSPn 51 189
Pfam A DSPc 239 366
disorder n/a 404 425
disorder n/a 427 438
disorder n/a 461 488
low_complexity n/a 472 494

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O60729. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKRKSERRSS WAAAPPCSRR CSSTSPGVKK IRSSTQQDPR RRDPQDDVYL
50
51
DITDRLCFAI LYSRPKSASN VHYFSIDNEL EYENFYADFG PLNLAMVYRY
100
101
CCKINKKLKS ITMLRKKIVH FTGSDQRKQA NAAFLVGCYM VIYLGRTPEE
150
151
AYRILIFGET SYIPFRDAAY GSCNFYITLL DCFHAVKKAM QYGFLNFNSF
200
201
NLDEYEHYEK AENGDLNWII PDRFIAFCGP HSRARLESGY HQHSPETYIQ
250
251
YFKNHNVTTI IRLNKRMYDA KRFTDAGFDH HDLFFADGST PTDAIVKEFL
300
301
DICENAEGAI AVHCKAGLGR TGTLIACYIM KHYRMTAAET IAWVRICRPG
350
351
SVIGPQQQFL VMKQTNLWLE GDYFRQKLKG QENGQHRAAF SKLLSGVDDI
400
401
SINGVENQDQ QEPEPYSDDD EINGVTQGDR LRALKSRRQS KTNAIPLTVI
450
451
LQSSVQSCKT SEPNISGSAG ITKRTTRSAS RKSSVKSLSI SRTKTVLR  
498
 

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Checksums:
CRC64:CEE15EC4DC3B1DC7
MD5:9ee0a23d9d497c0885ecfe9c7d09d8f5

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
DSPc 239 - 366 1OHC A 239 - 366 Jmol AstexViewer SPICE
1OHD A 239 - 366 Jmol AstexViewer SPICE
1OHE A 239 - 366 Jmol AstexViewer SPICE
DSPn 51 - 189 1OHC A 51 - 189 Jmol AstexViewer SPICE
1OHD A 51 - 189 Jmol AstexViewer SPICE
1OHE A 51 - 189 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.