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16  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HPGDS_HUMAN (O60760)

Summary

This is the summary of UniProt entry HPGDS_HUMAN (O60760).

Description: Hematopoietic prostaglandin D synthase EC=5.3.99.2 EC=2.5.1.18
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 199 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A GST_N 4 73
Pfam A GST_C 81 185

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O60760. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPNYKLTYFN MRGRAEIIRY IFAYLDIQYE DHRIEQADWP EIKSTLPFGK
50
51
IPILEVDGLT LHQSLAIARY LTKNTDLAGN TEMEQCHVDA IVDTLDDFMS
100
101
CFPWAEKKQD VKEQMFNELL TYNAPHLMQD LDTYLGGREW LIGNSVTWAD
150
151
FYWEICSTTL LVFKPDLLDN HPRLVTLRKK VQAIPAVANW IKRRPQTKL 
199
 

Show the unformatted sequence.

Checksums:
CRC64:A4ED2476B16CC5C3
MD5:a12e61cb43117a662f6206dfe991eaac

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
GST_C 81 - 185 1IYH A 81 - 185 Jmol AstexViewer SPICE
B 281 - 385 Jmol AstexViewer SPICE
C 481 - 585 Jmol AstexViewer SPICE
D 681 - 785 Jmol AstexViewer SPICE
1IYI A 81 - 185 Jmol AstexViewer SPICE
B 281 - 385 Jmol AstexViewer SPICE
C 481 - 585 Jmol AstexViewer SPICE
D 681 - 785 Jmol AstexViewer SPICE
1V40 A 81 - 185 Jmol AstexViewer SPICE
B 281 - 385 Jmol AstexViewer SPICE
C 481 - 585 Jmol AstexViewer SPICE
D 681 - 785 Jmol AstexViewer SPICE
2CVD A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
2VCQ A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
2VCW A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
2VCX A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
2VCZ A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
2VD0 A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
2VD1 A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
3EE2 A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
3KXO A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
3VI5 A 81 - 185 Jmol AstexViewer SPICE
B 281 - 385 Jmol AstexViewer SPICE
C 481 - 585 Jmol AstexViewer SPICE
D 681 - 785 Jmol AstexViewer SPICE
3VI7 A 81 - 185 Jmol AstexViewer SPICE
B 281 - 385 Jmol AstexViewer SPICE
C 481 - 585 Jmol AstexViewer SPICE
D 681 - 785 Jmol AstexViewer SPICE
4EC0 A 81 - 185 Jmol AstexViewer SPICE
B 1081 - 1185 Jmol AstexViewer SPICE
4EDZ A 81 - 185 Jmol AstexViewer SPICE
B 81 - 185 Jmol AstexViewer SPICE
C 81 - 185 Jmol AstexViewer SPICE
D 81 - 185 Jmol AstexViewer SPICE
GST_N 4 - 73 1IYH A 4 - 73 Jmol AstexViewer SPICE
B 204 - 273 Jmol AstexViewer SPICE
C 404 - 473 Jmol AstexViewer SPICE
D 604 - 673 Jmol AstexViewer SPICE
1IYI A 4 - 73 Jmol AstexViewer SPICE
B 204 - 273 Jmol AstexViewer SPICE
C 404 - 473 Jmol AstexViewer SPICE
D 604 - 673 Jmol AstexViewer SPICE
1V40 A 4 - 73 Jmol AstexViewer SPICE
B 204 - 273 Jmol AstexViewer SPICE
C 404 - 473 Jmol AstexViewer SPICE
D 604 - 673 Jmol AstexViewer SPICE
2CVD A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE
2VCQ A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE
2VCW A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE
2VCX A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE
2VCZ A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE
2VD0 A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE
2VD1 A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE
3EE2 A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
3KXO A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
3VI5 A 4 - 73 Jmol AstexViewer SPICE
B 204 - 273 Jmol AstexViewer SPICE
C 404 - 473 Jmol AstexViewer SPICE
D 604 - 673 Jmol AstexViewer SPICE
3VI7 A 4 - 73 Jmol AstexViewer SPICE
B 204 - 273 Jmol AstexViewer SPICE
C 404 - 473 Jmol AstexViewer SPICE
D 604 - 673 Jmol AstexViewer SPICE
4EC0 A 4 - 73 Jmol AstexViewer SPICE
B 1004 - 1073 Jmol AstexViewer SPICE
4EDZ A 4 - 73 Jmol AstexViewer SPICE
B 4 - 73 Jmol AstexViewer SPICE
C 4 - 73 Jmol AstexViewer SPICE
D 4 - 73 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.