Summary
This is the summary of UniProt entry FZD7_HUMAN (O75084).
| Description: | Frizzled-7 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 574 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 32 |
| low_complexity | n/a | 10 | 32 |
| Pfam A | Fz | 49 | 161 |
| disorder | n/a | 164 | 167 |
| disorder | n/a | 170 | 176 |
| low_complexity | n/a | 170 | 184 |
| Pfam A | Frizzled | 243 | 567 |
| transmembrane | n/a | 255 | 277 |
| transmembrane | n/a | 289 | 309 |
| transmembrane | n/a | 338 | 363 |
| transmembrane | n/a | 383 | 402 |
| transmembrane | n/a | 422 | 448 |
| transmembrane | n/a | 469 | 492 |
| transmembrane | n/a | 527 | 549 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O75084. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MRDPGAAAPL SSLGLCALVL ALLGALSAGA GAQPYHGEKG ISVPDHGFCQ
50 51
PISIPLCTDI AYNQTILPNL LGHTNQEDAG LEVHQFYPLV KVQCSPELRF
100 101
FLCSMYAPVC TVLDQAIPPC RSLCERARQG CEALMNKFGF QWPERLRCEN
150 151
FPVHGAGEIC VGQNTSDGSG GPGGGPTAYP TAPYLPDLPF TALPPGASDG
200 201
RGRPAFPFSC PRQLKVPPYL GYRFLGERDC GAPCEPGRAN GLMYFKEEER
250 251
RFARLWVGVW SVLCCASTLF TVLTYLVDMR RFSYPERPII FLSGCYFMVA
300 301
VAHVAGFLLE DRAVCVERFS DDGYRTVAQG TKKEGCTILF MVLYFFGMAS
350 351
SIWWVILSLT WFLAAGMKWG HEAIEANSQY FHLAAWAVPA VKTITILAMG
400 401
QVDGDLLSGV CYVGLSSVDA LRGFVLAPLF VYLFIGTSFL LAGFVSLFRI
450 451
RTIMKHDGTK TEKLEKLMVR IGVFSVLYTV PATIVLACYF YEQAFREHWE
500 501
RTWLLQTCKS YAVPCPPGHF PPMSPDFTVF MIKYLMTMIV GITTGFWIWS
550 551
GKTLQSWRRF YHRLSHSSKG ETAV
574
Show the unformatted sequence. |
| Checksums: |
CRC64:801934246B426DF5
MD5:3694d9f8a7f7fce5fa124b0797ea9e63
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.