Summary
This is the summary of UniProt entry SLIT1_HUMAN (O75093).
| Description: | Slit homolog 1 protein |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1534 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 33 |
| low_complexity | n/a | 18 | 33 |
| Pfam A | LRRNT | 33 | 60 |
| Pfam A | LRR_8 | 61 | 121 |
| Pfam A | LRR_8 | 109 | 169 |
| low_complexity | n/a | 110 | 119 |
| Pfam A | LRR_8 | 157 | 217 |
| low_complexity | n/a | 186 | 196 |
| Pfam A | LRRCT | 239 | 264 |
| Pfam A | LRRNT | 281 | 308 |
| Pfam A | LRR_8 | 333 | 393 |
| low_complexity | n/a | 380 | 388 |
| Pfam A | LRR_8 | 382 | 441 |
| Pfam A | LRRCT | 463 | 488 |
| Pfam A | LRRNT | 512 | 539 |
| Pfam A | LRR_1 | 566 | 588 |
| Pfam A | LRR_8 | 589 | 649 |
| Pfam A | LRR_8 | 613 | 673 |
| Pfam A | LRRCT | 695 | 720 |
| Pfam A | LRRNT | 733 | 760 |
| Pfam A | LRR_8 | 761 | 820 |
| Pfam A | LRR_8 | 784 | 844 |
| low_complexity | n/a | 792 | 808 |
| Pfam A | LRR_8 | 808 | 868 |
| low_complexity | n/a | 831 | 839 |
| Pfam A | LRRCT | 890 | 915 |
| Pfam A | EGF | 929 | 960 |
| Pfam A | EGF | 1047 | 1079 |
| Pfam A | EGF | 1080 | 1117 |
| Pfam A | Laminin_G_2 | 1194 | 1322 |
| Pfam A | hEGF | 1400 | 1412 |
| Pfam A | hEGF | 1441 | 1453 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession O75093. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MALTPGWGSS AGPVRPELWL LLWAAAWRLG ASACPALCTC TGTTVDCHGT
50 51
GLQAIPKNIP RNTERLELNG NNITRIHKND FAGLKQLRVL QLMENQIGAV
100 101
ERGAFDDMKE LERLRLNRNQ LHMLPELLFQ NNQALSRLDL SENAIQAIPR
150 151
KAFRGATDLK NLQLDKNQIS CIEEGAFRAL RGLEVLTLNN NNITTIPVSS
200 201
FNHMPKLRTF RLHSNHLFCD CHLAWLSQWL RQRPTIGLFT QCSGPASLRG
250 251
LNVAEVQKSE FSCSGQGEAG RVPTCTLSSG SCPAMCTCSN GIVDCRGKGL
300 301
TAIPANLPET MTEIRLELNG IKSIPPGAFS PYRKLRRIDL SNNQIAEIAP
350 351
DAFQGLRSLN SLVLYGNKIT DLPRGVFGGL YTLQLLLLNA NKINCIRPDA
400 401
FQDLQNLSLL SLYDNKIQSL AKGTFTSLRA IQTLHLAQNP FICDCNLKWL
450 451
ADFLRTNPIE TSGARCASPR RLANKRIGQI KSKKFRCSAK EQYFIPGTED
500 501
YQLNSECNSD VVCPHKCRCE ANVVECSSLK LTKIPERIPQ STAELRLNNN
550 551
EISILEATGM FKKLTHLKKI NLSNNKVSEI EDGAFEGAAS VSELHLTANQ
600 601
LESIRSGMFR GLDGLRTLML RNNRISCIHN DSFTGLRNVR LLSLYDNQIT
650 651
TVSPGAFDTL QSLSTLNLLA NPFNCNCQLA WLGGWLRKRK IVTGNPRCQN
700 701
PDFLRQIPLQ DVAFPDFRCE EGQEEGGCLP RPQCPQECAC LDTVVRCSNK
750 751
HLRALPKGIP KNVTELYLDG NQFTLVPGQL STFKYLQLVD LSNNKISSLS
800 801
NSSFTNMSQL TTLILSYNAL QCIPPLAFQG LRSLRLLSLH GNDISTLQEG
850 851
IFADVTSLSH LAIGANPLYC DCHLRWLSSW VKTGYKEPGI ARCAGPQDME
900 901
GKLLLTTPAK KFECQGPPTL AVQAKCDLCL SSPCQNQGTC HNDPLEVYRC
950 951
ACPSGYKGRD CEVSLDSCSS GPCENGGTCH AQEGEDAPFT CSCPTGFEGP
1000 1001
TCGVNTDDCV DHACANGGVC VDGVGNYTCQ CPLQYEGKAC EQLVDLCSPD
1050 1051
LNPCQHEAQC VGTPDGPRCE CMPGYAGDNC SENQDDCRDH RCQNGAQCMD
1100 1101
EVNSYSCLCA EGYSGQLCEI PPHLPAPKSP CEGTECQNGA NCVDQGNRPV
1150 1151
CQCLPGFGGP ECEKLLSVNF VDRDTYLQFT DLQNWPRANI TLQVSTAEDN
1200 1201
GILLYNGDND HIAVELYQGH VRVSYDPGSY PSSAIYSAET INDGQFHTVE
1250 1251
LVAFDQMVNL SIDGGSPMTM DNFGKHYTLN SEAPLYVGGM PVDVNSAAFR
1300 1301
LWQILNGTGF HGCIRNLYIN NELQDFTKTQ MKPGVVPGCE PCRKLYCLHG
1350 1351
ICQPNATPGP MCHCEAGWVG LHCDQPADGP CHGHKCVHGQ CVPLDALSYS
1400 1401
CQCQDGYSGA LCNQAGALAE PCRGLQCLHG HCQASGTKGA HCVCDPGFSG
1450 1451
ELCEQESECR GDPVRDFHQV QRGYAICQTT RPLSWVECRG SCPGQGCCQG
1500 1501
LRLKRRKFTF ECSDGTSFAE EVEKPTKCGC ALCA
1534
Show the unformatted sequence. |
| Checksums: |
CRC64:47B11CE6704A3E1D
MD5:3bbd1b76c863cf770b7c6f607741d286
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.