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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: REM1_HUMAN (O75628)

Summary

This is the summary of UniProt entry REM1_HUMAN (O75628).

Description: GTP-binding protein REM 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 298 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 72
low_complexity n/a 59 79
Pfam A Ras 82 245
disorder n/a 96 100
disorder n/a 103 104
disorder n/a 111 119
disorder n/a 247 263
low_complexity n/a 251 291

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession O75628. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTLNTEQEAK TPLHRRASTP LPLSPRGHQP GRLSTVPSTQ SQHPRLGQSA
50
51
SLNPPTQKPS PAPDDWSSES SDSEGSWEAL YRVVLLGDPG VGKTSLASLF
100
101
AGKQERDLHE QLGEDVYERT LTVDGEDTTL VVVDTWEAEK LDKSWSQESC
150
151
LQGGSAYVIV YSIADRGSFE SASELRIQLR RTHQADHVPI ILVGNKADLA
200
201
RCREVSVEEG RACAVVFDCK FIETSATLQH NVAELFEGVV RQLRLRRRDS
250
251
AAKEPPAPRR PASLAQRARR FLARLTARSA RRRALKARSK SCHNLAVL  
298
 

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Checksums:
CRC64:E7CCE776FFD42CD7
MD5:78f3c16930816bdc52c5ea54c89610ae

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ras 82 - 245 2NZJ A 82 - 245 Jmol AstexViewer SPICE
B 82 - 245 Jmol AstexViewer SPICE
C 82 - 245 Jmol AstexViewer SPICE
D 82 - 245 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.