Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPOD_ECOLI (P00579)

Summary

This is the summary of UniProt entry RPOD_ECOLI (P00579).

Description: RNA polymerase sigma factor rpoD
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 613 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Sigma70_r1_1 1 81
disorder n/a 3 10
disorder n/a 23 24
disorder n/a 28 29
disorder n/a 32 33
disorder n/a 35 36
disorder n/a 59 73
low_complexity n/a 72 81
disorder n/a 77 88
disorder n/a 94 99
Pfam A Sigma70_r1_2 95 130
disorder n/a 103 105
Pfam A Sigma70_ner 137 348
disorder n/a 159 216
low_complexity n/a 188 209
coiled_coil n/a 330 350
Pfam A Sigma70_r2 379 449
Pfam A Sigma70_r3 458 535
disorder n/a 468 486
disorder n/a 509 511
disorder n/a 513 514
disorder n/a 534 535
Pfam A Sigma70_r4 547 600
coiled_coil n/a 573 593

Show or hide domain scores.

Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

Note: it can take a few seconds for this image to be generated and loaded.

Loading feature alignment...

Show sources update panel.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P00579. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEQNPQSQLK LLVTRGKEQG YLTYAEVNDH LPEDIVDSDQ IEDIIQMIND
50
51
MGIQVMEEAP DADDLMLAEN TADEDAAEAA AQVLSSVESE IGRTTDPVRM
100
101
YMREMGTVEL LTREGEIDIA KRIEDGINQV QCSVAEYPEA ITYLLEQYDR
150
151
VEAEEARLSD LITGFVDPNA EEDLAPTATH VGSELSQEDL DDDEDEDEED
200
201
GDDDSADDDN SIDPELAREK FAELRAQYVV TRDTIKAKGR SHATAQEEIL
250
251
KLSEVFKQFR LVPKQFDYLV NSMRVMMDRV RTQERLIMKL CVEQCKMPKK
300
301
NFITLFTGNE TSDTWFNAAI AMNKPWSEKL HDVSEEVHRA LQKLQQIEEE
350
351
TGLTIEQVKD INRRMSIGEA KARRAKKEMV EANLRLVISI AKKYTNRGLQ
400
401
FLDLIQEGNI GLMKAVDKFE YRRGYKFSTY ATWWIRQAIT RSIADQARTI
450
451
RIPVHMIETI NKLNRISRQM LQEMGREPTP EELAERMLMP EDKIRKVLKI
500
501
AKEPISMETP IGDDEDSHLG DFIEDTTLEL PLDSATTESL RAATHDVLAG
550
551
LTAREAKVLR MRFGIDMNTD YTLEEVGKQF DVTRERIRQI EAKALRKLRH
600
601
PSRSEVLRSF LDD                                        
613
 

Show the unformatted sequence.

Checksums:
CRC64:CA4F0E30DEC1703D
MD5:76c71bc8c46d1acced17d1ca3625783a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Sigma70_ner 137 - 348 1SIG A 137 - 348 Jmol AstexViewer SPICE
3IYD F 137 - 348 Jmol AstexViewer SPICE
Sigma70_r1_2 105 - 130 3IYD F 113 - 130 Jmol AstexViewer SPICE
114 - 130 1SIG A 114 - 130 Jmol AstexViewer SPICE
Sigma70_r2 379 - 446 1SIG A 379 - 446 Jmol AstexViewer SPICE
379 - 449 3IYD F 379 - 449 Jmol AstexViewer SPICE
Sigma70_r3 458 - 535 3IYD F 458 - 535 Jmol AstexViewer SPICE
Sigma70_r4 547 - 600 1TLH B 547 - 600 Jmol AstexViewer SPICE
2P7V B 547 - 600 Jmol AstexViewer SPICE
3IYD F 547 - 600 Jmol AstexViewer SPICE