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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: KLK2_RAT (P00759)

Summary

This is the summary of UniProt entry KLK2_RAT (P00759).

Description: Tonin EC=3.4.21.35
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
View Pfam proteome data.
Length: 259 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 17
Pfam A Trypsin 25 251
disorder n/a 115 116

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P00759. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MWLQILSLVL SVGRIDAAPP GQSRIVGGYK CEKNSQPWQV AVINEYLCGG
50
51
VLIDPSWVIT AAHCYSNNYQ VLLGRNNLFK DEPFAQRRLV RQSFRHPDYI
100
101
PLIVTNDTEQ PVHDHSNDLM LLHLSEPADI TGGVKVIDLP TKEPKVGSTC
150
151
LASGWGSTNP SEMVVSHDLQ CVNIHLLSNE KCIETYKDNV TDVMLCAGEM
200
201
EGGKDTCAGD SGGPLICDGV LQGITSGGAT PCAKPKTPAI YAKLIKFTSW
250
251
IKKVMKENP                                             
259
 

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Checksums:
CRC64:3D6E60D011F926B4
MD5:db55ad383c7316610e74ab316dca77f1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Trypsin 25 - 251 1TON A 16 - 238 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.