Summary
This is the summary of UniProt entry THER_BACTH (P00800).
| Description: | Thermolysin EC=3.4.24.27 |
| Source organism: |
Bacillus thermoproteolyticus
(NCBI taxonomy ID
1427)
|
| Length: | 548 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 28 |
| low_complexity | n/a | 11 | 18 |
| coiled_coil | n/a | 65 | 85 |
| Pfam A | FTP | 81 | 130 |
| low_complexity | n/a | 136 | 146 |
| Pfam A | PepSY | 144 | 219 |
| low_complexity | n/a | 234 | 247 |
| Pfam A | Peptidase_M4 | 236 | 383 |
| Pfam A | Peptidase_M4_C | 385 | 547 |
| disorder | n/a | 436 | 437 |
| disorder | n/a | 440 | 441 |
| disorder | n/a | 445 | 452 |
| disorder | n/a | 454 | 456 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P00800. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MKMKMKLASF GLAAGLAAQV FLPYNALAST EHVTWNQQFQ TPQFISGDLL
50 51
KVNGTSPEEL VYQYVEKNEN KFKFHENAKD TLQLKEKKND NLGFTFMRFQ
100 101
QTYKGIPVFG AVVTSHVKDG TLTALSGTLI PNLDTKGSLK SGKKLSEKQA
150 151
RDIAEKDLVA NVTKEVPEYE QGKDTEFVVY VNGDEASLAY VVNLNFLTPE
200 201
PGNWLYIIDA VDGKILNKFN QLDAAKPGDV KSITGTSTVG VGRGVLGDQK
250 251
NINTTYSTYY YLQDNTRGNG IFTYDAKYRT TLPGSLWADA DNQFFASYDA
300 301
PAVDAHYYAG VTYDYYKNVH NRLSYDGNNA AIRSSVHYSQ GYNNAFWNGS
350 351
QMVYGDGDGQ TFIPLSGGID VVAHELTHAV TDYTAGLIYQ NESGAINEAI
400 401
SDIFGTLVEF YANKNPDWEI GEDVYTPGIS GDSLRSMSDP AKYGDPDHYS
450 451
KRYTGTQDNG GVHINSGIIN KAAYLISQGG THYGVSVVGI GRDKLGKIFY
500 501
RALTQYLTPT SNFSQLRAAA VQSATDLYGS TSQEVASVKQ AFDAVGVK
548
Show the unformatted sequence. |
| Checksums: |
CRC64:1D6ED3A545F045C8
MD5:d620e4555780063a6def792ba0be7a82
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.