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17  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CAH1_HUMAN (P00915)

Summary

This is the summary of UniProt entry CAH1_HUMAN (P00915).

Description: Carbonic anhydrase 1 EC=4.2.1.1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 261 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 2 8
Pfam A Carb_anhydrase 6 261
disorder n/a 17 24
disorder n/a 28 40
disorder n/a 45 48
disorder n/a 238 258

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P00915. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASPDWGYDD KNGPEQWSKL YPIANGNNQS PVDIKTSETK HDTSLKPISV
50
51
SYNPATAKEI INVGHSFHVN FEDNDNRSVL KGGPFSDSYR LFQFHFHWGS
100
101
TNEHGSEHTV DGVKYSAELH VAHWNSAKYS SLAEAASKAD GLAVIGVLMK
150
151
VGEANPKLQK VLDALQAIKT KGKRAPFTNF DPSTLLPSSL DFWTYPGSLT
200
201
HPPLYESVTW IICKESISVS SEQLAQFRSL LSNVEGDNAV PMQHNNRPTQ
250
251
PLKGRTVRAS F                                          
261
 

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Checksums:
CRC64:4959E5FA25E374F8
MD5:f32824489822ce88a5e7097c9bd957bd

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Carb_anhydrase 6 - 260 1AZM A 5 - 259 Jmol AstexViewer SPICE
1BZM A 5 - 259 Jmol AstexViewer SPICE
1CRM A 5 - 259 Jmol AstexViewer SPICE
1CZM A 5 - 259 Jmol AstexViewer SPICE
1HCB A 5 - 259 Jmol AstexViewer SPICE
1HUG A 5 - 259 Jmol AstexViewer SPICE
1HUH A 5 - 259 Jmol AstexViewer SPICE
1J9W A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
1JV0 A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
2CAB A 5 - 259 Jmol AstexViewer SPICE
2FOY A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
2FW4 A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
2IT4 A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
2NMX A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
2NN1 A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
2NN7 A 5 - 259 Jmol AstexViewer SPICE
B 5 - 259 Jmol AstexViewer SPICE
6 - 261 3LXE A 5 - 260 Jmol AstexViewer SPICE
B 5 - 260 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.