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102  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RASH_HUMAN (P01112)

Summary

This is the summary of UniProt entry RASH_HUMAN (P01112).

Description: GTPase HRas
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 189 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Ras 5 165
low_complexity n/a 7 15
disorder n/a 168 172

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P01112. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
50
51
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI
100
101
KRVKDSDDVP MVLVGNKCDL AARTVESRQA QDLARSYGIP YIETSAKTRQ
150
151
GVEDAFYTLV REIRQHKLRK LNPPDESGPG CMSCKCVLS            
189
 

Show the unformatted sequence.

Checksums:
CRC64:EE6DC2D933E2856A
MD5:90e23ca169b65f2b833159b51cda20c3

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Ras 5 - 164 2X1V A 5 - 164 Jmol AstexViewer SPICE
5 - 165 121P A 5 - 165 Jmol AstexViewer SPICE
1AA9 A 5 - 165 Jmol AstexViewer SPICE
1AGP A 5 - 165 Jmol AstexViewer SPICE
1BKD R 5 - 165 Jmol AstexViewer SPICE
1CLU A 5 - 165 Jmol AstexViewer SPICE
1CRP A 5 - 165 Jmol AstexViewer SPICE
1CRQ A 5 - 165 Jmol AstexViewer SPICE
1CRR A 5 - 165 Jmol AstexViewer SPICE
1CTQ A 5 - 165 Jmol AstexViewer SPICE
1GNP A 5 - 165 Jmol AstexViewer SPICE
1GNQ A 5 - 165 Jmol AstexViewer SPICE
1GNR A 5 - 165 Jmol AstexViewer SPICE
1IAQ A 5 - 165 Jmol AstexViewer SPICE
B 5 - 165 Jmol AstexViewer SPICE
C 5 - 165 Jmol AstexViewer SPICE
1IOZ A 5 - 165 Jmol AstexViewer SPICE
1JAH A 5 - 165 Jmol AstexViewer SPICE
1JAI A 5 - 165 Jmol AstexViewer SPICE
1K8R A 5 - 165 Jmol AstexViewer SPICE
1LF0 A 5 - 165 Jmol AstexViewer SPICE
1LF5 A 5 - 165 Jmol AstexViewer SPICE
1LFD B 205 - 365 Jmol AstexViewer SPICE
D 205 - 365 Jmol AstexViewer SPICE
1NVU Q 5 - 165 Jmol AstexViewer SPICE
R 5 - 165 Jmol AstexViewer SPICE
1NVV Q 5 - 165 Jmol AstexViewer SPICE
R 5 - 165 Jmol AstexViewer SPICE
1NVW Q 5 - 165 Jmol AstexViewer SPICE
R 5 - 165 Jmol AstexViewer SPICE
1NVX Q 5 - 165 Jmol AstexViewer SPICE
R 5 - 165 Jmol AstexViewer SPICE
1P2S A 5 - 165 Jmol AstexViewer SPICE
1P2T A 5 - 165 Jmol AstexViewer SPICE
1P2U A 5 - 165 Jmol AstexViewer SPICE
1P2V A 5 - 165 Jmol AstexViewer SPICE
1PLJ A 5 - 165 Jmol AstexViewer SPICE
1PLK A 5 - 165 Jmol AstexViewer SPICE
1PLL A 5 - 165 Jmol AstexViewer SPICE
1Q21 A 5 - 165 Jmol AstexViewer SPICE
1QRA A 5 - 165 Jmol AstexViewer SPICE
1RVD A 5 - 165 Jmol AstexViewer SPICE
1WQ1 R 5 - 165 Jmol AstexViewer SPICE
1XCM A 5 - 165 Jmol AstexViewer SPICE
1XD2 A 5 - 165 Jmol AstexViewer SPICE
B 5 - 165 Jmol AstexViewer SPICE
1XJ0 A 5 - 165 Jmol AstexViewer SPICE
1ZVQ A 5 - 165 Jmol AstexViewer SPICE
1ZW6 A 5 - 165 Jmol AstexViewer SPICE
221P A 5 - 165 Jmol AstexViewer SPICE
2C5L A 5 - 165 Jmol AstexViewer SPICE
B 5 - 165 Jmol AstexViewer SPICE
2CE2 X 5 - 165 Jmol AstexViewer SPICE
2CL0 X 5 - 165 Jmol AstexViewer SPICE
2CL6 X 5 - 165 Jmol AstexViewer SPICE
2CL7 X 5 - 165 Jmol AstexViewer SPICE
2CLC X 5 - 165 Jmol AstexViewer SPICE
2CLD X 5 - 165 Jmol AstexViewer SPICE
2EVW X 5 - 165 Jmol AstexViewer SPICE
2LCF A 5 - 165 Jmol AstexViewer SPICE
2Q21 A 5 - 165 Jmol AstexViewer SPICE
2QUZ A 5 - 165 Jmol AstexViewer SPICE
2RGA A 5 - 165 Jmol AstexViewer SPICE
2RGB A 5 - 165 Jmol AstexViewer SPICE
2RGC A 5 - 165 Jmol AstexViewer SPICE
2RGD A 5 - 165 Jmol AstexViewer SPICE
2RGE A 5 - 165 Jmol AstexViewer SPICE
2RGG A 5 - 165 Jmol AstexViewer SPICE
2UZI R 5 - 165 Jmol AstexViewer SPICE
2VH5 R 5 - 165 Jmol AstexViewer SPICE
3DDC A 5 - 165 Jmol AstexViewer SPICE
3I3S R 5 - 165 Jmol AstexViewer SPICE
3K8Y A 5 - 165 Jmol AstexViewer SPICE
3K9L A 5 - 165 Jmol AstexViewer SPICE
B 5 - 165 Jmol AstexViewer SPICE
C 5 - 165 Jmol AstexViewer SPICE
3K9N A 5 - 165 Jmol AstexViewer SPICE
3KKM A 5 - 165 Jmol AstexViewer SPICE
3KKN A 5 - 165 Jmol AstexViewer SPICE
3KUD A 5 - 165 Jmol AstexViewer SPICE
3L8Y A 5 - 165 Jmol AstexViewer SPICE
3L8Z A 5 - 165 Jmol AstexViewer SPICE
3LBH A 5 - 165 Jmol AstexViewer SPICE
3LBI A 5 - 165 Jmol AstexViewer SPICE
3LBN A 5 - 165 Jmol AstexViewer SPICE
3LO5 A 5 - 165 Jmol AstexViewer SPICE
C 5 - 165 Jmol AstexViewer SPICE
E 5 - 165 Jmol AstexViewer SPICE
3OIU A 5 - 165 Jmol AstexViewer SPICE
3OIV A 5 - 165 Jmol AstexViewer SPICE
3OIW A 5 - 165 Jmol AstexViewer SPICE
3RRY A 5 - 165 Jmol AstexViewer SPICE
3RRZ A 5 - 165 Jmol AstexViewer SPICE
3RS0 A 5 - 165 Jmol AstexViewer SPICE
3RS2 A 5 - 165 Jmol AstexViewer SPICE
3RS3 A 5 - 165 Jmol AstexViewer SPICE
3RS4 A 5 - 165 Jmol AstexViewer SPICE
3RS5 A 5 - 165 Jmol AstexViewer SPICE
3RS7 A 5 - 165 Jmol AstexViewer SPICE
3RSL A 5 - 165 Jmol AstexViewer SPICE
3RSO A 5 - 165 Jmol AstexViewer SPICE
3TGP A 5 - 165 Jmol AstexViewer SPICE
421P A 5 - 165 Jmol AstexViewer SPICE
4DST A 5 - 165 Jmol AstexViewer SPICE
4DSU A 5 - 165 Jmol AstexViewer SPICE
4EFL A 5 - 165 Jmol AstexViewer SPICE
4EFM A 5 - 165 Jmol AstexViewer SPICE
4EFN A 5 - 165 Jmol AstexViewer SPICE
4Q21 A 5 - 165 Jmol AstexViewer SPICE
521P A 5 - 165 Jmol AstexViewer SPICE
5P21 A 5 - 165 Jmol AstexViewer SPICE
621P A 5 - 165 Jmol AstexViewer SPICE
6Q21 A 5 - 165 Jmol AstexViewer SPICE
B 5 - 165 Jmol AstexViewer SPICE
C 5 - 165 Jmol AstexViewer SPICE
D 5 - 165 Jmol AstexViewer SPICE
721P A 5 - 165 Jmol AstexViewer SPICE
821P A 5 - 165 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.