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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DQA1_HUMAN (P01909)

Summary

This is the summary of UniProt entry DQA1_HUMAN (P01909).

Description: HLA class II histocompatibility antigen, DQ alpha 1 chain
Source organism: Homo sapiens (Human)
Length: 254 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 23
Pfam A MHC_II_alpha 29 109
Pfam A C1-set 118 200
transmembrane n/a 221 239
low_complexity n/a 222 241

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P01909. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MILNKALMLG ALALTTVMSP CGGEDIVADH VASYGVNLYQ SYGPSGQYTH
50
51
EFDGDEQFYV DLGRKETVWC LPVLRQFRFD PQFALTNIAV LKHNLNSLIK
100
101
RSNSTAATNE VPEVTVFSKS PVTLGQPNIL ICLVDNIFPP VVNITWLSNG
150
151
HSVTEGVSET SFLSKSDHSF FKISYLTLLP SAEESYDCKV EHWGLDKPLL
200
201
KHWEPEIPAP MSELTETVVC ALGLSVGLVG IVVGTVFIIR GLRSVGASRH
250
251
QGPL                                                  
254
 

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Checksums:
CRC64:84E12B5A80E2A028
MD5:3020800c0f1a3e5f3da33f3eaa1f17fe

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
C1-set 118 - 200 1JK8 A 93 - 175 Jmol AstexViewer SPICE
1S9V A 93 - 175 Jmol AstexViewer SPICE
D 93 - 175 Jmol AstexViewer SPICE
2NNA A 93 - 175 Jmol AstexViewer SPICE
MHC_II_alpha 29 - 109 1JK8 A 4 - 84 Jmol AstexViewer SPICE
1S9V A 4 - 84 Jmol AstexViewer SPICE
D 4 - 84 Jmol AstexViewer SPICE
2NNA A 4 - 84 Jmol AstexViewer SPICE