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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NEF_HV1BR (P03406)

Summary

This is the summary of UniProt entry NEF_HV1BR (P03406).

Description: Protein Nef
Source organism: Human immunodeficiency virus type 1 group M subtype B (isolate BRU/LAI) (HIV-1) (NCBI taxonomy ID 11686)
View Pfam proteome data.
Length: 206 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A F-protein 2 205
disorder n/a 16 18
disorder n/a 21 44
low_complexity n/a 42 56
disorder n/a 68 71
disorder n/a 156 161
disorder n/a 164 169

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P03406. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGGKWSKSSV VGWPTVRERM RRAEPAADGV GAASRDLEKH GAITSSNTAA
50
51
TNAACAWLEA QEEEEVGFPV TPQVPLRPMT YKAAVDLSHF LKEKGGLEGL
100
101
IHSQRRQDIL DLWIYHTQGY FPDWQNYTPG PGVRYPLTFG WCYKLVPVEP
150
151
DKVEEANKGE NTSLLHPVSL HGMDDPEREV LEWRFDSRLA FHHVARELHP
200
201
EYFKNC                                                
206
 

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Checksums:
CRC64:77453FC80B6004F2
MD5:bdbbdcd65dc55bbcde4e7acb1fcbd542

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
F-protein 71 - 203 1AVZ B 71 - 203 Jmol AstexViewer SPICE
1EFN B 71 - 203 Jmol AstexViewer SPICE
D 71 - 203 Jmol AstexViewer SPICE
74 - 203 1AVV A 74 - 203 Jmol AstexViewer SPICE
1AVZ A 74 - 203 Jmol AstexViewer SPICE