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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HA2D_MOUSE (P04228)

Summary

This is the summary of UniProt entry HA2D_MOUSE (P04228).

Description: H-2 class II histocompatibility antigen, A-D alpha chain
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
View Pfam proteome data.
Length: 256 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 23
Pfam A MHC_II_alpha 30 111
disorder n/a 111 112
Pfam A C1-set 120 202
transmembrane n/a 223 241
low_complexity n/a 224 241
disorder n/a 252 256

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P04228. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPCSRALILG VLALNTMLSL CGGEDDIEAD HVGFYGTTVY QSPGDIGQYT
50
51
HEFDGDELFY VDLDKKKTVW RLPEFGQLIL FEPQGGLQNI AAEKHNLGIL
100
101
TKRSNFTPAT NEAPQATVFP KSPVLLGQPN TLICFVDNIF PPVINITWLR
150
151
NSKSVTDGVY ETSFLVNRDH SFHKLSYLTF IPSDDDIYDC KVEHWGLEEP
200
201
VLKHWEPEIP APMSELTETV VCALGLSVGL VGIVVGTIFI IQGLRSGGTS
250
251
RHPGPL                                                
256
 

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Checksums:
CRC64:085B3FE643B58BBB
MD5:30487389a37f218424a3e75beefb9d80

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
C1-set 120 - 202 1ES0 A 93 - 175 Jmol AstexViewer SPICE
1F3J A 93 - 175 Jmol AstexViewer SPICE
D 93 - 175 Jmol AstexViewer SPICE
2IAD A 93 - 175 Jmol AstexViewer SPICE
3CUP A 93 - 175 Jmol AstexViewer SPICE
3MBE A 93 - 175 Jmol AstexViewer SPICE
E 93 - 175 Jmol AstexViewer SPICE
MHC_II_alpha 30 - 111 1ES0 A 3 - 84 Jmol AstexViewer SPICE
1F3J A 4 - 84 Jmol AstexViewer SPICE
D 4 - 84 Jmol AstexViewer SPICE
2IAD A 3 - 84 Jmol AstexViewer SPICE
3CUP A 3 - 84 Jmol AstexViewer SPICE
3MBE A 3 - 84 Jmol AstexViewer SPICE
E 3 - 84 Jmol AstexViewer SPICE