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32  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: 2B11_HUMAN (P04229)

Summary

This is the summary of UniProt entry 2B11_HUMAN (P04229).

Description: HLA class II histocompatibility antigen, DRB1-1 beta chain
Source organism: Homo sapiens (Human)
Length: 266 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 29
Pfam A MHC_II_beta 42 116
Pfam A C1-set 132 214
transmembrane n/a 228 250
low_complexity n/a 229 247

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P04229. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVCLKLPGGS CMTALTVTLM VLSSPLALAG DTRPRFLWQL KFECHFFNGT
50
51
ERVRLLERCI YNQEESVRFD SDVGEYRAVT ELGRPDAEYW NSQKDLLEQR
100
101
RAAVDTYCRH NYGVGESFTV QRRVEPKVTV YPSKTQPLQH HNLLVCSVSG
150
151
FYPGSIEVRW FRNGQEEKAG VVSTGLIQNG DWTFQTLVML ETVPRSGEVY
200
201
TCQVEHPSVT SPLTVEWRAR SESAQSKMLS GVGGFVLGLL FLGAGLFIYF
250
251
RNQKGHSGLQ PTGFLS                                     
266
 

Show the unformatted sequence.

Checksums:
CRC64:CC9CC7E2D0DD036C
MD5:0e71902bd429bd63422e1de7cd6ffd21

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
C1-set 132 - 214 1AQD B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
H 103 - 185 Jmol AstexViewer SPICE
K 103 - 185 Jmol AstexViewer SPICE
1DLH B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
1FYT B 103 - 185 Jmol AstexViewer SPICE
1HXY B 103 - 185 Jmol AstexViewer SPICE
1JWM B 103 - 185 Jmol AstexViewer SPICE
1JWS B 103 - 185 Jmol AstexViewer SPICE
1JWU B 103 - 185 Jmol AstexViewer SPICE
1KG0 B 103 - 185 Jmol AstexViewer SPICE
1KLG B 103 - 185 Jmol AstexViewer SPICE
1KLU B 103 - 185 Jmol AstexViewer SPICE
1LO5 B 103 - 185 Jmol AstexViewer SPICE
1SEB B 103 - 185 Jmol AstexViewer SPICE
F 103 - 185 Jmol AstexViewer SPICE
1SJE B 103 - 185 Jmol AstexViewer SPICE
1SJH B 103 - 185 Jmol AstexViewer SPICE
1T5W B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
1T5X B 103 - 185 Jmol AstexViewer SPICE
2FSE B 103 - 185 Jmol AstexViewer SPICE
D 103 - 185 Jmol AstexViewer SPICE
2G9H B 103 - 185 Jmol AstexViewer SPICE
2IAM B 103 - 185 Jmol AstexViewer SPICE
2IAN B 103 - 185 Jmol AstexViewer SPICE
G 103 - 185 Jmol AstexViewer SPICE
L 103 - 185 Jmol AstexViewer SPICE
Q 103 - 185 Jmol AstexViewer SPICE
2ICW B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
2IPK B 103 - 185 Jmol AstexViewer SPICE
2OJE B 103 - 185 Jmol AstexViewer SPICE
F 103 - 185 Jmol AstexViewer SPICE
2XN9 E 103 - 185 Jmol AstexViewer SPICE
3L6F B 103 - 185 Jmol AstexViewer SPICE
3PDO B 103 - 185 Jmol AstexViewer SPICE
3PGC B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
3PGD B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
3QXA B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
3QXD B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
3S4S B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
3S5L B 103 - 185 Jmol AstexViewer SPICE
E 103 - 185 Jmol AstexViewer SPICE
MHC_II_beta 42 - 116 1AQD B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
H 13 - 87 Jmol AstexViewer SPICE
K 13 - 87 Jmol AstexViewer SPICE
1DLH B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
1FYT B 13 - 87 Jmol AstexViewer SPICE
1HXY B 13 - 87 Jmol AstexViewer SPICE
1JWM B 13 - 87 Jmol AstexViewer SPICE
1JWS B 13 - 87 Jmol AstexViewer SPICE
1JWU B 13 - 87 Jmol AstexViewer SPICE
1KG0 B 13 - 87 Jmol AstexViewer SPICE
1KLG B 13 - 87 Jmol AstexViewer SPICE
1KLU B 13 - 87 Jmol AstexViewer SPICE
1LO5 B 13 - 87 Jmol AstexViewer SPICE
1SEB B 13 - 87 Jmol AstexViewer SPICE
F 13 - 87 Jmol AstexViewer SPICE
1SJE B 13 - 87 Jmol AstexViewer SPICE
1SJH B 13 - 87 Jmol AstexViewer SPICE
1T5W B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
1T5X B 13 - 87 Jmol AstexViewer SPICE
2FSE B 13 - 87 Jmol AstexViewer SPICE
D 13 - 87 Jmol AstexViewer SPICE
2G9H B 13 - 87 Jmol AstexViewer SPICE
2IAM B 13 - 87 Jmol AstexViewer SPICE
2IAN B 13 - 87 Jmol AstexViewer SPICE
G 13 - 87 Jmol AstexViewer SPICE
L 13 - 87 Jmol AstexViewer SPICE
Q 13 - 87 Jmol AstexViewer SPICE
2ICW B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
2IPK B 13 - 87 Jmol AstexViewer SPICE
2OJE B 13 - 87 Jmol AstexViewer SPICE
F 13 - 87 Jmol AstexViewer SPICE
2XN9 E 13 - 87 Jmol AstexViewer SPICE
3L6F B 13 - 87 Jmol AstexViewer SPICE
3PDO B 13 - 87 Jmol AstexViewer SPICE
3PGC B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
3PGD B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
3QXA B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
3QXD B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
3S4S B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE
3S5L B 13 - 87 Jmol AstexViewer SPICE
E 13 - 87 Jmol AstexViewer SPICE