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22  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ALDH2_HUMAN (P05091)

Summary

This is the summary of UniProt entry ALDH2_HUMAN (P05091).

Description: Aldehyde dehydrogenase, mitochondrial EC=1.2.1.3
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 517 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 26
disorder n/a 19 23
Pfam A Aldedh 45 508
low_complexity n/a 72 86
disorder n/a 350 356
disorder n/a 358 359

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P05091. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLRAAARFGP RLGRRLLSAA ATQAVPAPNQ QPEVFCNQIF INNEWHDAVS
50
51
RKTFPTVNPS TGEVICQVAE GDKEDVDKAV KAARAAFQLG SPWRRMDASH
100
101
RGRLLNRLAD LIERDRTYLA ALETLDNGKP YVISYLVDLD MVLKCLRYYA
150
151
GWADKYHGKT IPIDGDFFSY TRHEPVGVCG QIIPWNFPLL MQAWKLGPAL
200
201
ATGNVVVMKV AEQTPLTALY VANLIKEAGF PPGVVNIVPG FGPTAGAAIA
250
251
SHEDVDKVAF TGSTEIGRVI QVAAGSSNLK RVTLELGGKS PNIIMSDADM
300
301
DWAVEQAHFA LFFNQGQCCC AGSRTFVQED IYDEFVERSV ARAKSRVVGN
350
351
PFDSKTEQGP QVDETQFKKI LGYINTGKQE GAKLLCGGGI AADRGYFIQP
400
401
TVFGDVQDGM TIAKEEIFGP VMQILKFKTI EEVVGRANNS TYGLAAAVFT
450
451
KDLDKANYLS QALQAGTVWV NCYDVFGAQS PFGGYKMSGS GRELGEYGLQ
500
501
AYTEVKTVTV KVPQKNS                                    
517
 

Show the unformatted sequence.

Checksums:
CRC64:E8F74D44D285A00E
MD5:bb50a3c1e7d4c85b428643cbedaba376

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Aldedh 45 - 508 1CW3 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1NZW A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1NZX A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1NZZ A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1O00 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1O01 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1O02 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1O04 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1O05 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
1ZUM A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
I 28 - 491 Jmol AstexViewer SPICE
J 28 - 491 Jmol AstexViewer SPICE
K 28 - 491 Jmol AstexViewer SPICE
L 28 - 491 Jmol AstexViewer SPICE
2ONM A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
I 28 - 491 Jmol AstexViewer SPICE
J 28 - 491 Jmol AstexViewer SPICE
K 28 - 491 Jmol AstexViewer SPICE
L 28 - 491 Jmol AstexViewer SPICE
2ONN A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
2ONO A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
2ONP A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
2VLE A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
3INJ A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
3INL A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
3N80 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
3N81 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
3N82 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
3N83 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE
3SZ9 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
E 28 - 491 Jmol AstexViewer SPICE
F 28 - 491 Jmol AstexViewer SPICE
G 28 - 491 Jmol AstexViewer SPICE
H 28 - 491 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.