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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FAS1_YEAST (P07149)

Summary

This is the summary of UniProt entry FAS1_YEAST (P07149).

Description: Fatty acid synthase subunit beta 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase Enoyl-[acyl-carrier-protein] reductase [NADH] [Acyl-carrier-protein] acetyltransferase [Acyl-carrier-protein] malonyltransferase S-acyl fatty acid synthase thioesterase EC=2.3.1.86 EC=4.2.1.61 EC=1.3.1.9 EC=2.3.1.38 EC=2.3.1.39 EC=3.1.2.14
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 2051 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 44 49
disorder n/a 51 53
disorder n/a 325 327
disorder n/a 339 340
disorder n/a 352 353
disorder n/a 355 356
Pfam A DUF1729 1018 1074
low_complexity n/a 1106 1124
disorder n/a 1114 1115
disorder n/a 1195 1197
Pfam A MaoC_dehydrat_N 1282 1406
low_complexity n/a 1463 1474
Pfam A MaoC_dehydratas 1522 1650
disorder n/a 1556 1557
Pfam A Acyl_transf_1 1663 2037
disorder n/a 1677 1678

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P07149. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDAYSTRPLT LSHGSLEHVL LVPTASFFIA SQLQEQFNKI LPEPTEGFAA
50
51
DDEPTTPAEL VGKFLGYVSS LVEPSKVGQF DQVLNLCLTE FENCYLEGND
100
101
IHALAAKLLQ ENDTTLVKTK ELIKNYITAR IMAKRPFDKK SNSALFRAVG
150
151
EGNAQLVAIF GGQGNTDDYF EELRDLYQTY HVLVGDLIKF SAETLSELIR
200
201
TTLDAEKVFT QGLNILEWLE NPSNTPDKDY LLSIPISCPL IGVIQLAHYV
250
251
VTAKLLGFTP GELRSYLKGA TGHSQGLVTA VAIAETDSWE SFFVSVRKAI
300
301
TVLFFIGVRC YEAYPNTSLP PSILEDSLEN NEGVPSPMLS ISNLTQEQVQ
350
351
DYVNKTNSHL PAGKQVEISL VNGAKNLVVS GPPQSLYGLN LTLRKAKAPS
400
401
GLDQSRIPFS ERKLKFSNRF LPVASPFHSH LLVPASDLIN KDLVKNNVSF
450
451
NAKDIQIPVY DTFDGSDLRV LSGSISERIV DCIIRLPVKW ETTTQFKATH
500
501
ILDFGPGGAS GLGVLTHRNK DGTGVRVIVA GTLDINPDDD YGFKQEIFDV
550
551
TSNGLKKNPN WLEEYHPKLI KNKSGKIFVE TKFSKLIGRP PLLVPGMTPC
600
601
TVSPDFVAAT TNAGYTIELA GGGYFSAAGM TAAIDSVVSQ IEKGSTFGIN
650
651
LIYVNPFMLQ WGIPLIKELR SKGYPIQFLT IGAGVPSLEV ASEYIETLGL
700
701
KYLGLKPGSI DAISQVINIA KAHPNFPIAL QWTGGRGGGH HSFEDAHTPM
750
751
LQMYSKIRRH PNIMLIFGSG FGSADDTYPY LTGEWSTKFD YPPMPFDGFL
800
801
FGSRVMIAKE VKTSPDAKKC IAACTGVPDD KWEQTYKKPT GGIVTVRSEM
850
851
GEPIHKIATR GVMLWKEFDE TIFNLPKNKL VPTLEAKRDY IISRLNADFQ
900
901
KPWFATVNGQ ARDLATMTYE EVAKRLVELM FIRSTNSWFD VTWRTFTGDF
950
951
LRRVEERFTK SKTLSLIQSY SLLDKPDEAI EKVFNAYPAA REQFLNAQDI
1000
1001
DHFLSMCQNP MQKPVPFVPV LDRRFEIFFK KDSLWQSEHL EAVVDQDVQR
1050
1051
TCILHGPVAA QFTKVIDEPI KSIMDGIHDG HIKKLLHQYY GDDESKIPAV
1100
1101
EYFGGESPVD VQSQVDSSSV SEDSAVFKAT SSTDEESWFK ALAGSEINWR
1150
1151
HASFLCSFIT QDKMFVSNPI RKVFKPSQGM VVEISNGNTS SKTVVTLSEP
1200
1201
VQGELKPTVI LKLLKENIIQ MEMIENRTMD GKPVSLPLLY NFNPDNGFAP
1250
1251
ISEVMEDRNQ RIKEMYWKLW IDEPFNLDFD PRDVIKGKDF EITAKEVYDF
1300
1301
THAVGNNCED FVSRPDRTML APMDFAIVVG WRAIIKAIFP NTVDGDLLKL
1350
1351
VHLSNGYKMI PGAKPLQVGD VVSTTAVIES VVNQPTGKIV DVVGTLSRNG
1400
1401
KPVMEVTSSF FYRGNYTDFE NTFQKTVEPV YQMHIKTSKD IAVLRSKEWF
1450
1451
QLDDEDFDLL NKTLTFETET EVTFKNANIF SSVKCFGPIK VELPTKETVE
1500
1501
IGIVDYEAGA SHGNPVVDFL KRNGSTLEQK VNLENPIPIA VLDSYTPSTN
1550
1551
EPYARVSGDL NPIHVSRHFA SYANLPGTIT HGMFSSASVR ALIENWAADS
1600
1601
VSSRVRGYTC QFVDMVLPNT ALKTSIQHVG MINGRKLIKF ETRNEDDVVV
1650
1651
LTGEAEIEQP VTTFVFTGQG SQEQGMGMDL YKTSKAAQDV WNRADNHFKD
1700
1701
TYGFSILDIV INNPVNLTIH FGGEKGKRIR ENYSAMIFET IVDGKLKTEK
1750
1751
IFKEINEHST SYTFRSEKGL LSATQFTQPA LTLMEKAAFE DLKSKGLIPA
1800
1801
DATFAGHSLG EYAALASLAD VMSIESLVEV VFYRGMTMQV AVPRDELGRS
1850
1851
NYGMIAINPG RVAASFSQEA LQYVVERVGK RTGWLVEIVN YNVENQQYVA
1900
1901
AGDLRALDTV TNVLNFIKLQ KIDIIELQKS LSLEEVEGHL FEIIDEASKK
1950
1951
SAVKPRPLKL ERGFACIPLV GISVPFHSTY LMNGVKPFKS FLKKNIIKEN
2000
2001
VKVARLAGKY IPNLTAKPFQ VTKEYFQDVY DLTGSEPIKE IIDNWEKYEQ
2050
2051
S                                                     
2051
 

Show the unformatted sequence.

Checksums:
CRC64:43AA85A6071D8EAA
MD5:c1332d2b5d3c8fb0a09a47874d6c5e5c

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Acyl_transf_1 1663 - 2037 2UV8 G 1663 - 2037 Jmol AstexViewer SPICE
H 1663 - 2037 Jmol AstexViewer SPICE
I 1663 - 2037 Jmol AstexViewer SPICE
2VKZ G 1663 - 2037 Jmol AstexViewer SPICE
H 1663 - 2037 Jmol AstexViewer SPICE
I 1663 - 2037 Jmol AstexViewer SPICE
3HMJ G 1663 - 2037 Jmol AstexViewer SPICE
H 1663 - 2037 Jmol AstexViewer SPICE
I 1663 - 2037 Jmol AstexViewer SPICE
DUF1729 1018 - 1074 2UV8 G 1018 - 1074 Jmol AstexViewer SPICE
H 1018 - 1074 Jmol AstexViewer SPICE
I 1018 - 1074 Jmol AstexViewer SPICE
2VKZ G 1018 - 1074 Jmol AstexViewer SPICE
H 1018 - 1074 Jmol AstexViewer SPICE
I 1018 - 1074 Jmol AstexViewer SPICE
3HMJ G 1018 - 1074 Jmol AstexViewer SPICE
H 1018 - 1074 Jmol AstexViewer SPICE
I 1018 - 1074 Jmol AstexViewer SPICE
MaoC_dehydrat_N 1282 - 1406 2UV8 G 1282 - 1406 Jmol AstexViewer SPICE
H 1282 - 1406 Jmol AstexViewer SPICE
I 1282 - 1406 Jmol AstexViewer SPICE
2VKZ G 1282 - 1406 Jmol AstexViewer SPICE
H 1282 - 1406 Jmol AstexViewer SPICE
I 1282 - 1406 Jmol AstexViewer SPICE
3HMJ G 1282 - 1406 Jmol AstexViewer SPICE
H 1282 - 1406 Jmol AstexViewer SPICE
I 1282 - 1406 Jmol AstexViewer SPICE
MaoC_dehydratas 1522 - 1650 2UV8 G 1522 - 1650 Jmol AstexViewer SPICE
H 1522 - 1650 Jmol AstexViewer SPICE
I 1522 - 1650 Jmol AstexViewer SPICE
2VKZ G 1522 - 1650 Jmol AstexViewer SPICE
H 1522 - 1650 Jmol AstexViewer SPICE
I 1522 - 1650 Jmol AstexViewer SPICE
3HMJ G 1522 - 1650 Jmol AstexViewer SPICE
H 1522 - 1650 Jmol AstexViewer SPICE
I 1522 - 1650 Jmol AstexViewer SPICE