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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: ANXA6_HUMAN (P08133)

Summary

This is the summary of UniProt entry ANXA6_HUMAN (P08133).

Description: Annexin A6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 673 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Annexin 24 89
Pfam A Annexin 96 161
Pfam A Annexin 179 245
Pfam A Annexin 255 320
Pfam A Annexin 367 432
low_complexity n/a 381 391
Pfam A Annexin 439 504
disorder n/a 443 446
disorder n/a 484 485
disorder n/a 511 520
Pfam A Annexin 524 593
disorder n/a 530 531
Pfam A Annexin 603 668

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P08133. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAKPAQGAKY RGSIHDFPGF DPNQDAEALY TAMKGFGSDK EAILDIITSR
50
51
SNRQRQEVCQ SYKSLYGKDL IADLKYELTG KFERLIVGLM RPPAYCDAKE
100
101
IKDAISGIGT DEKCLIEILA SRTNEQMHQL VAAYKDAYER DLEADIIGDT
150
151
SGHFQKMLVV LLQGTREEDD VVSEDLVQQD VQDLYEAGEL KWGTDEAQFI
200
201
YILGNRSKQH LRLVFDEYLK TTGKPIEASI RGELSGDFEK LMLAVVKCIR
250
251
STPEYFAERL FKAMKGLGTR DNTLIRIMVS RSELDMLDIR EIFRTKYEKS
300
301
LYSMIKNDTS GEYKKTLLKL SGGDDDAAGQ FFPEAAQVAY QMWELSAVAR
350
351
VELKGTVRPA NDFNPDADAK ALRKAMKGLG TDEDTIIDII THRSNVQRQQ
400
401
IRQTFKSHFG RDLMTDLKSE ISGDLARLIL GLMMPPAHYD AKQLKKAMEG
450
451
AGTDEKALIE ILATRTNAEI RAINEAYKED YHKSLEDALS SDTSGHFRRI
500
501
LISLATGHRE EGGENLDQAR EDAQVAAEIL EIADTPSGDK TSLETRFMTI
550
551
LCTRSYPHLR RVFQEFIKMT NYDVEHTIKK EMSGDVRDAF VAIVQSVKNK
600
601
PLFFADKLYK SMKGAGTDEK TLTRIMVSRS EIDLLNIRRE FIEKYDKSLH
650
651
QAIEGDTSGD FLKALLALCG GED                             
673
 

Show the unformatted sequence.

Checksums:
CRC64:90F47474F7F6D7B6
MD5:79789a99a477518899eafc4a0cd18b10

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Annexin 179 - 245 1M9I A 179 - 245 Jmol AstexViewer SPICE
24 - 89 1M9I A 24 - 89 Jmol AstexViewer SPICE
255 - 320 1M9I A 255 - 320 Jmol AstexViewer SPICE
367 - 432 1M9I A 367 - 432 Jmol AstexViewer SPICE
439 - 504 1M9I A 439 - 504 Jmol AstexViewer SPICE
524 - 593 1M9I A 524 - 593 Jmol AstexViewer SPICE
603 - 668 1M9I A 603 - 668 Jmol AstexViewer SPICE
96 - 161 1M9I A 96 - 161 Jmol AstexViewer SPICE