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7  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: UCHL1_HUMAN (P09936)

Summary

This is the summary of UniProt entry UCHL1_HUMAN (P09936).

Description: Ubiquitin carboxyl-terminal hydrolase isozyme L1 EC=3.4.19.12 EC=6.-.-.-
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 223 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Peptidase_C12 2 208
low_complexity n/a 43 55
disorder n/a 66 67

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P09936. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQLKPMEINP EMLNKVLSRL GVAGQWRFVD VLGLEEESLG SVPAPACALL
50
51
LLFPLTAQHE NFRKKQIEEL KGQEVSPKVY FMKQTIGNSC GTIGLIHAVA
100
101
NNQDKLGFED GSVLKQFLSE TEKMSPEDRA KCFEKNEAIQ AAHDAVAQEG
150
151
QCRVDDKVNF HFILFNNVDG HLYELDGRMP FPVNHGASSE DTLLKDAAKV
200
201
CREFTEREQG EVRFSAVALC KAA                             
223
 

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Checksums:
CRC64:C9E972AC4DA5DA8A
MD5:4e2d951802809da36a75a5bdb77b1f74

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Peptidase_C12 2 - 208 2ETL A 2 - 208 Jmol AstexViewer SPICE
B 2 - 208 Jmol AstexViewer SPICE
2LEN A 2 - 208 Jmol AstexViewer SPICE
3IFW A 2 - 208 Jmol AstexViewer SPICE
3IRT A 2 - 208 Jmol AstexViewer SPICE
B 2 - 208 Jmol AstexViewer SPICE
3KVF A 2 - 208 Jmol AstexViewer SPICE
3KW5 A 2 - 208 Jmol AstexViewer SPICE
4DM9 A 2 - 208 Jmol AstexViewer SPICE
B 2 - 208 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.