Summary
This is the summary of UniProt entry PKNB_MYCTU (P0A5S4).
| Description: | Serine/threonine-protein kinase pknB EC=2.7.11.1 |
| Source organism: |
Mycobacterium tuberculosis
(NCBI taxonomy ID
1773)
View Pfam proteome data. |
| Length: | 626 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam A | Pkinase | 11 | 274 |
| disorder | n/a | 187 | 188 |
| disorder | n/a | 220 | 240 |
| low_complexity | n/a | 243 | 257 |
| disorder | n/a | 266 | 292 |
| low_complexity | n/a | 295 | 306 |
| disorder | n/a | 298 | 323 |
| transmembrane | n/a | 332 | 353 |
| low_complexity | n/a | 333 | 350 |
| Pfam A | PASTA | 360 | 422 |
| disorder | n/a | 361 | 362 |
| disorder | n/a | 364 | 365 |
| disorder | n/a | 367 | 371 |
| disorder | n/a | 385 | 389 |
| disorder | n/a | 391 | 408 |
| disorder | n/a | 411 | 425 |
| Pfam A | PASTA | 427 | 490 |
| disorder | n/a | 428 | 429 |
| disorder | n/a | 431 | 432 |
| disorder | n/a | 451 | 452 |
| disorder | n/a | 460 | 472 |
| Pfam A | PASTA | 495 | 557 |
| disorder | n/a | 498 | 502 |
| disorder | n/a | 526 | 549 |
| Pfam A | PASTA | 561 | 626 |
| disorder | n/a | 590 | 592 |
| disorder | n/a | 597 | 610 |
| disorder | n/a | 616 | 618 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P0A5S4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MTTPSHLSDR YELGEILGFG GMSEVHLARD LRLHRDVAVK VLRADLARDP
50 51
SFYLRFRREA QNAAALNHPA IVAVYDTGEA ETPAGPLPYI VMEYVDGVTL
100 101
RDIVHTEGPM TPKRAIEVIA DACQALNFSH QNGIIHRDVK PANIMISATN
150 151
AVKVMDFGIA RAIADSGNSV TQTAAVIGTA QYLSPEQARG DSVDARSDVY
200 201
SLGCVLYEVL TGEPPFTGDS PVSVAYQHVR EDPIPPSARH EGLSADLDAV
250 251
VLKALAKNPE NRYQTAAEMR ADLVRVHNGE PPEAPKVLTD AERTSLLSSA
300 301
AGNLSGPRTD PLPRQDLDDT DRDRSIGSVG RWVAVVAVLA VLTVVVTIAI
350 351
NTFGGITRDV QVPDVRGQSS ADAIATLQNR GFKIRTLQKP DSTIPPDHVI
400 401
GTDPAANTSV SAGDEITVNV STGPEQREIP DVSTLTYAEA VKKLTAAGFG
450 451
RFKQANSPST PELVGKVIGT NPPANQTSAI TNVVIIIVGS GPATKDIPDV
500 501
AGQTVDVAQK NLNVYGFTKF SQASVDSPRP AGEVTGTNPP AGTTVPVDSV
550 551
IELQVSKGNQ FVMPDLSGMF WVDAEPRLRA LGWTGMLDKG ADVDAGGSQH
600 601
NRVVYQNPPA GTGVNRDGII TLRFGQ
626
Show the unformatted sequence. |
| Checksums: |
CRC64:6C27EEBE9D5A453B
MD5:234d021001b8b0cf9fcbf16338163317
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.
| Pfam family | UniProt residues | PDB ID | PDB chain ID | PDB residues | View |
|---|---|---|---|---|---|
| PASTA | 360 - 422 | 2KUD | A | 360 - 422 | Jmol AstexViewer SPICE |
| 2KUI | A | 360 - 422 | Jmol AstexViewer SPICE | ||
| 427 - 490 | 2KUD | A | 427 - 490 | Jmol AstexViewer SPICE | |
| 2KUE | A | 427 - 490 | Jmol AstexViewer SPICE | ||
| 2KUI | A | 427 - 490 | Jmol AstexViewer SPICE | ||
| 495 - 557 | 2KUE | A | 495 - 557 | Jmol AstexViewer SPICE | |
| 2KUF | A | 495 - 557 | Jmol AstexViewer SPICE | ||
| 2KUI | A | 495 - 557 | Jmol AstexViewer SPICE | ||
| 561 - 626 | 2KUF | A | 561 - 626 | Jmol AstexViewer SPICE | |
| 2KUI | A | 561 - 626 | Jmol AstexViewer SPICE | ||
| Pkinase | 11 - 274 | 1MRU | A | 11 - 274 | Jmol AstexViewer SPICE |
| B | 11 - 274 | Jmol AstexViewer SPICE | |||
| 1O6Y | A | 11 - 274 | Jmol AstexViewer SPICE | ||
| 2FUM | A | 11 - 274 | Jmol AstexViewer SPICE | ||
| B | 11 - 274 | Jmol AstexViewer SPICE | |||
| C | 11 - 274 | Jmol AstexViewer SPICE | |||
| D | 11 - 274 | Jmol AstexViewer SPICE | |||
| 3F61 | A | 11 - 274 | Jmol AstexViewer SPICE | ||
| 3F69 | A | 11 - 274 | Jmol AstexViewer SPICE | ||
| B | 11 - 274 | Jmol AstexViewer SPICE |