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9  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPOA_ECOLI (P0A7Z4)

Summary

This is the summary of UniProt entry RPOA_ECOLI (P0A7Z4).

Description: DNA-directed RNA polymerase subunit alpha EC=2.7.7.6
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 329 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A RNA_pol_L 28 229
Pfam A RNA_pol_A_bac 58 186
disorder n/a 155 159
disorder n/a 203 205
Pfam A RNA_pol_A_CTD 243 309

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P0A7Z4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MQGSVTEFLK PRLVDIEQVS STHAKVTLEP LERGFGHTLG NALRRILLSS
50
51
MPGCAVTEVE IDGVLHEYST KEGVQEDILE ILLNLKGLAV RVQGKDEVIL
100
101
TLNKSGIGPV TAADITHDGD VEIVKPQHVI CHLTDENASI SMRIKVQRGR
150
151
GYVPASTRIH SEEDERPIGR LLVDACYSPV ERIAYNVEAA RVEQRTDLDK
200
201
LVIEMETNGT IDPEEAIRRA ATILAEQLEA FVDLRDVRQP EVKEEKPEFD
250
251
PILLRPVDDL ELTVRSANCL KAEAIHYIGD LVQRTEVELL KTPNLGKKSL
300
301
TEIKDVLASR GLSLGMRLEN WPPASIADE                       
329
 

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Checksums:
CRC64:12A14B75A3CAEA19
MD5:456bfd9236c5cfd90803aed14a8ec2d0

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RNA_pol_A_bac 58 - 186 1BDF A 58 - 186 Jmol AstexViewer SPICE
B 58 - 186 Jmol AstexViewer SPICE
C 58 - 186 Jmol AstexViewer SPICE
D 58 - 186 Jmol AstexViewer SPICE
3IYD A 58 - 186 Jmol AstexViewer SPICE
B 58 - 186 Jmol AstexViewer SPICE
3LU0 A 58 - 186 Jmol AstexViewer SPICE
B 58 - 186 Jmol AstexViewer SPICE
RNA_pol_A_CTD 243 - 309 3IYD A 243 - 309 Jmol AstexViewer SPICE
246 - 309 3K4G A 246 - 309 Jmol AstexViewer SPICE
B 246 - 309 Jmol AstexViewer SPICE
C 246 - 309 Jmol AstexViewer SPICE
D 246 - 309 Jmol AstexViewer SPICE
E 246 - 309 Jmol AstexViewer SPICE
F 246 - 309 Jmol AstexViewer SPICE
G 246 - 309 Jmol AstexViewer SPICE
H 246 - 309 Jmol AstexViewer SPICE
249 - 309 1COO A 249 - 309 Jmol AstexViewer SPICE
1XS9 D 249 - 309 Jmol AstexViewer SPICE
3N4M B 249 - 309 Jmol AstexViewer SPICE
250 - 309 1LB2 B 250 - 309 Jmol AstexViewer SPICE
E 250 - 309 Jmol AstexViewer SPICE
3N4M C 250 - 309 Jmol AstexViewer SPICE
3N97 B 250 - 309 Jmol AstexViewer SPICE
C 250 - 309 Jmol AstexViewer SPICE
RNA_pol_L 28 - 229 1BDF A 28 - 229 Jmol AstexViewer SPICE
B 28 - 229 Jmol AstexViewer SPICE
C 28 - 229 Jmol AstexViewer SPICE
D 28 - 229 Jmol AstexViewer SPICE
3IYD A 28 - 229 Jmol AstexViewer SPICE
B 28 - 229 Jmol AstexViewer SPICE
3LU0 A 28 - 229 Jmol AstexViewer SPICE
B 28 - 229 Jmol AstexViewer SPICE