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4  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RPOC_ECOLI (P0A8T7)

Summary

This is the summary of UniProt entry RPOC_ECOLI (P0A8T7).

Description: DNA-directed RNA polymerase subunit beta' EC=2.7.7.6
Source organism: Escherichia coli (strain K12) (NCBI taxonomy ID 83333)
View Pfam proteome data.
Length: 1407 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A RNA_pol_Rpb1_1 14 342
coiled_coil n/a 184 218
low_complexity n/a 194 207
disorder n/a 200 210
low_complexity n/a 212 224
low_complexity n/a 241 256
low_complexity n/a 270 283
Pfam A RNA_pol_Rpb1_2 344 486
Pfam A RNA_pol_Rpb1_3 489 644
low_complexity n/a 652 669
Pfam A RNA_pol_Rpb1_4 673 764
disorder n/a 704 707
disorder n/a 709 710
Pfam A RNA_pol_Rpb1_5 766 1322
low_complexity n/a 940 949
low_complexity n/a 959 974
disorder n/a 1013 1019
disorder n/a 1118 1130
disorder n/a 1132 1133
disorder n/a 1176 1178
disorder n/a 1207 1211
coiled_coil n/a 1275 1295
disorder n/a 1368 1385
low_complexity n/a 1369 1381
low_complexity n/a 1389 1404

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P0A8T7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKDLLKFLKA QTKTEEFDAI KIALASPDMI RSWSFGEVKK PETINYRTFK
50
51
PERDGLFCAR IFGPVKDYEC LCGKYKRLKH RGVICEKCGV EVTQTKVRRE
100
101
RMGHIELASP TAHIWFLKSL PSRIGLLLDM PLRDIERVLY FESYVVIEGG
150
151
MTNLERQQIL TEEQYLDALE EFGDEFDAKM GAEAIQALLK SMDLEQECEQ
200
201
LREELNETNS ETKRKKLTKR IKLLEAFVQS GNKPEWMILT VLPVLPPDLR
250
251
PLVPLDGGRF ATSDLNDLYR RVINRNNRLK RLLDLAAPDI IVRNEKRMLQ
300
301
EAVDALLDNG RRGRAITGSN KRPLKSLADM IKGKQGRFRQ NLLGKRVDYS
350
351
GRSVITVGPY LRLHQCGLPK KMALELFKPF IYGKLELRGL ATTIKAAKKM
400
401
VEREEAVVWD ILDEVIREHP VLLNRAPTLH RLGIQAFEPV LIEGKAIQLH
450
451
PLVCAAYNAD FDGDQMAVHV PLTLEAQLEA RALMMSTNNI LSPANGEPII
500
501
VPSQDVVLGL YYMTRDCVNA KGEGMVLTGP KEAERLYRSG LASLHARVKV
550
551
RITEYEKDAN GELVAKTSLK DTTVGRAILW MIVPKGLPYS IVNQALGKKA
600
601
ISKMLNTCYR ILGLKPTVIF ADQIMYTGFA YAARSGASVG IDDMVIPEKK
650
651
HEIISEAEAE VAEIQEQFQS GLVTAGERYN KVIDIWAAAN DRVSKAMMDN
700
701
LQTETVINRD GQEEKQVSFN SIYMMADSGA RGSAAQIRQL AGMRGLMAKP
750
751
DGSIIETPIT ANFREGLNVL QYFISTHGAR KGLADTALKT ANSGYLTRRL
800
801
VDVAQDLVVT EDDCGTHEGI MMTPVIEGGD VKEPLRDRVL GRVTAEDVLK
850
851
PGTADILVPR NTLLHEQWCD LLEENSVDAV KVRSVVSCDT DFGVCAHCYG
900
901
RDLARGHIIN KGEAIGVIAA QSIGEPGTQL TMRTFHIGGA ASRAAAESSI
950
951
QVKNKGSIKL SNVKSVVNSS GKLVITSRNT ELKLIDEFGR TKESYKVPYG
1000
1001
AVLAKGDGEQ VAGGETVANW DPHTMPVITE VSGFVRFTDM IDGQTITRQT
1050
1051
DELTGLSSLV VLDSAERTAG GKDLRPALKI VDAQGNDVLI PGTDMPAQYF
1100
1101
LPGKAIVQLE DGVQISSGDT LARIPQESGG TKDITGGLPR VADLFEARRP
1150
1151
KEPAILAEIS GIVSFGKETK GKRRLVITPV DGSDPYEEMI PKWRQLNVFE
1200
1201
GERVERGDVI SDGPEAPHDI LRLRGVHAVT RYIVNEVQDV YRLQGVKIND
1250
1251
KHIEVIVRQM LRKATIVNAG SSDFLEGEQV EYSRVKIANR ELEANGKVGA
1300
1301
TYSRDLLGIT KASLATESFI SAASFQETTR VLTEAAVAGK RDELRGLKEN
1350
1351
VIVGRLIPAG TGYAYHQDRM RRRAAGEAPA APQVTAEDAS ASLAELLNAG
1400
1401
LGGSDNE                                               
1407
 

Show the unformatted sequence.

Checksums:
CRC64:A6878C61D15F4961
MD5:a30532fe425b21bf247cfa9b90939faa

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
RNA_pol_Rpb1_1 14 - 342 3LU0 D 14 - 342 Jmol AstexViewer SPICE
15 - 342 3IYD D 15 - 342 Jmol AstexViewer SPICE
RNA_pol_Rpb1_2 344 - 486 3IYD D 344 - 486 Jmol AstexViewer SPICE
3LU0 D 344 - 486 Jmol AstexViewer SPICE
RNA_pol_Rpb1_3 489 - 644 3IYD D 489 - 644 Jmol AstexViewer SPICE
3LU0 D 489 - 644 Jmol AstexViewer SPICE
RNA_pol_Rpb1_4 673 - 764 3IYD D 673 - 764 Jmol AstexViewer SPICE
3LU0 D 673 - 764 Jmol AstexViewer SPICE
RNA_pol_Rpb1_5 1153 - 1213 2LMC B 24 - 84 Jmol AstexViewer SPICE
766 - 1322 3IYD D 766 - 1322 Jmol AstexViewer SPICE
3LU0 D 766 - 1322 Jmol AstexViewer SPICE
944 - 1128 2AUK A 5 - 189 Jmol AstexViewer SPICE
E 5 - 189 Jmol AstexViewer SPICE
946 - 1128 2AUK C 7 - 189 Jmol AstexViewer SPICE
D 7 - 189 Jmol AstexViewer SPICE
947 - 1127 2AUK B 8 - 188 Jmol AstexViewer SPICE