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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: RARA_HUMAN (P10276)

Summary

This is the summary of UniProt entry RARA_HUMAN (P10276).

Description: Retinoic acid receptor alpha
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 462 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
disorder n/a 1 7
disorder n/a 11 12
low_complexity n/a 19 30
disorder n/a 46 47
disorder n/a 52 76
low_complexity n/a 65 80
Pfam A zf-C4 86 155
disorder n/a 159 166
Pfam A Hormone_recep 207 409
disorder n/a 346 349
disorder n/a 374 375
disorder n/a 407 462
low_complexity n/a 425 462

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P10276. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASNSSSCPT PGGGHLNGYP VPPYAFFFPP MLGGLSPPGA LTTLQHQLPV
50
51
SGYSTPSPAT IETQSSSSEE IVPSPPSPPP LPRIYKPCFV CQDKSSGYHY
100
101
GVSACEGCKG FFRRSIQKNM VYTCHRDKNC IINKVTRNRC QYCRLQKCFE
150
151
VGMSKESVRN DRNKKKKEVP KPECSESYTL TPEVGELIEK VRKAHQETFP
200
201
ALCQLGKYTT NNSSEQRVSL DIDLWDKFSE LSTKCIIKTV EFAKQLPGFT
250
251
TLTIADQITL LKAACLDILI LRICTRYTPE QDTMTFSDGL TLNRTQMHNA
300
301
GFGPLTDLVF AFANQLLPLE MDDAETGLLS AICLICGDRQ DLEQPDRVDM
350
351
LQEPLLEALK VYVRKRRPSR PHMFPKMLMK ITDLRSISAK GAERVITLKM
400
401
EIPGSMPPLI QEMLENSEGL DTLSGQPGGG GRDGGGLAPP PGSCSPSLSP
450
451
SSNRSSPATH SP                                         
462
 

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Checksums:
CRC64:E8D1CF9A1E57CB99
MD5:edeb62b89ac7410dacc89087e128843d

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Hormone_recep 207 - 401 3KMZ A 207 - 401 Jmol AstexViewer SPICE
B 207 - 401 Jmol AstexViewer SPICE
207 - 409 1DKF B 207 - 409 Jmol AstexViewer SPICE
3A9E B 207 - 409 Jmol AstexViewer SPICE
3KMR A 207 - 409 Jmol AstexViewer SPICE
zf-C4 87 - 155 1DSZ A 1134 - 1202 Jmol AstexViewer SPICE