Summary
This is the summary of UniProt entry CO6A1_HUMAN (P12109).
| Description: | Collagen alpha-1(VI) chain |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 1028 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| sig_p | n/a | 1 | 21 |
| low_complexity | n/a | 3 | 18 |
| Pfam A | VWA | 37 | 229 |
| disorder | n/a | 214 | 216 |
| disorder | n/a | 220 | 224 |
| disorder | n/a | 226 | 227 |
| disorder | n/a | 229 | 231 |
| Pfam A | Collagen | 253 | 313 |
| disorder | n/a | 254 | 255 |
| disorder | n/a | 257 | 593 |
| Pfam A | Collagen | 293 | 368 |
| low_complexity | n/a | 299 | 317 |
| Pfam A | Collagen | 347 | 419 |
| low_complexity | n/a | 380 | 413 |
| Pfam A | Collagen | 395 | 472 |
| low_complexity | n/a | 415 | 446 |
| Pfam A | Collagen | 449 | 517 |
| low_complexity | n/a | 455 | 471 |
| low_complexity | n/a | 482 | 506 |
| Pfam A | Collagen | 500 | 564 |
| low_complexity | n/a | 547 | 561 |
| low_complexity | n/a | 575 | 591 |
| Pfam A | VWA | 615 | 793 |
| disorder | n/a | 725 | 729 |
| disorder | n/a | 737 | 739 |
| Pfam A | VWA | 829 | 1016 |
| disorder | n/a | 875 | 877 |
| disorder | n/a | 953 | 955 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P12109. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MRAARALLPL LLQACWTAAQ DEPETPRAVA FQDCPVDLFF VLDTSESVAL
50 51
RLKPYGALVD KVKSFTKRFI DNLRDRYYRC DRNLVWNAGA LHYSDEVEII
100 101
QGLTRMPGGR DALKSSVDAV KYFGKGTYTD CAIKKGLEQL LVGGSHLKEN
150 151
KYLIVVTDGH PLEGYKEPCG GLEDAVNEAK HLGVKVFSVA ITPDHLEPRL
200 201
SIIATDHTYR RNFTAADWGQ SRDAEEAISQ TIDTIVDMIK NNVEQVCCSF
250 251
ECQPARGPPG LRGDPGFEGE RGKPGLPGEK GEAGDPGRPG DLGPVGYQGM
300 301
KGEKGSRGEK GSRGPKGYKG EKGKRGIDGV DGVKGEMGYP GLPGCKGSPG
350 351
FDGIQGPPGP KGDPGAFGLK GEKGEPGADG EAGRPGSSGP SGDEGQPGEP
400 401
GPPGEKGEAG DEGNPGPDGA PGERGGPGER GPRGTPGTRG PRGDPGEAGP
450 451
QGDQGREGPV GVPGDPGEAG PIGPKGYRGD EGPPGSEGAR GAPGPAGPPG
500 501
DPGLMGERGE DGPAGNGTEG FPGFPGYPGN RGAPGINGTK GYPGLKGDEG
550 551
EAGDPGDDNN DIAPRGVKGA KGYRGPEGPQ GPPGHQGPPG PDECEILDII
600 601
MKMCSCCECK CGPIDLLFVL DSSESIGLQN FEIAKDFVVK VIDRLSRDEL
650 651
VKFEPGQSYA GVVQYSHSQM QEHVSLRSPS IRNVQELKEA IKSLQWMAGG
700 701
TFTGEALQYT RDQLLPPSPN NRIALVITDG RSDTQRDTTP LNVLCSPGIQ
750 751
VVSVGIKDVF DFIPGSDQLN VISCQGLAPS QGRPGLSLVK ENYAELLEDA
800 801
FLKNVTAQIC IDKKCPDYTC PITFSSPADI TILLDGSASV GSHNFDTTKR
850 851
FAKRLAERFL TAGRTDPAHD VRVAVVQYSG TGQQRPERAS LQFLQNYTAL
900 901
ASAVDAMDFI NDATDVNDAL GYVTRFYREA SSGAAKKRLL LFSDGNSQGA
950 951
TPAAIEKAVQ EAQRAGIEIF VVVVGRQVNE PHIRVLVTGK TAEYDVAYGE
1000 1001
SHLFRVPSYQ ALLRGVFHQT VSRKVALG
1028
Show the unformatted sequence. |
| Checksums: |
CRC64:04AFF538002A01CD
MD5:1b957047c698bac1aeb4aaa8cc0a3eb4
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.