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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GAG_HV1Z2 (P12495)

Summary

This is the summary of UniProt entry GAG_HV1Z2 (P12495).

Description: Gag polyprotein
Source organism: Human immunodeficiency virus type 1 group M subtype D (isolate Z2/CDC-Z34) (HIV-1) (NCBI taxonomy ID 11683)
Length: 501 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A Gag_p17 2 133
coiled_coil n/a 87 121
disorder n/a 97 127
low_complexity n/a 102 128
disorder n/a 130 132
disorder n/a 134 135
Pfam A Gag_p24 150 364
disorder n/a 176 177
disorder n/a 184 192
disorder n/a 199 201
disorder n/a 203 204
disorder n/a 212 213
disorder n/a 217 241
disorder n/a 244 245
disorder n/a 249 250
disorder n/a 362 367
disorder n/a 375 382
Pfam A zf-CCHC 392 409
Pfam A zf-CCHC 413 430
disorder n/a 436 439
disorder n/a 444 487
Pfam A Gag_p6 451 487

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P12495. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGARASVLSG GKLDAWEKIR LRPGGKKKYR LKHLVWASRE LERFALNPGL
50
51
LETSDGCKQI IGQLQPAIRT GSEELRSLFN TVATLYCVHE RIEVKDTKEA
100
101
LEKMEEEQNK SKNKKAQQAA ADAGNNSQVS QNYPIVQNLQ GQMVHQAISP
150
151
RTLNAWVKVI EEKAFSPEVI PMFSALSEGA TPQDLNTMLN TVGGHQAAMQ
200
201
MLKETINEEA AEWDRLHPVH AGPIAPGQMR EPRGSDIAGT TSTLQEQIAW
250
251
MTSNPPIPVG EIYKRWIILG LNKIVRMYSP VSILDIRQGP KEPFRDYVDR
300
301
FYKTLRAEQA SQEVKGWMTE TLLVQNANPD CKTILKALGP QATLEEMMTA
350
351
CQGVGGPSHK ARVLAEAMSQ ATNSAAAVMM QRGNFKGPRK TIKCFNCGKE
400
401
GHIAKNCRAP RRKGCWKCGK EGHQLKDCTE RQANFLGKIW PSHKGRPGNF
450
451
LQSRPEPTAP PAESFGFGEE ITPSQKQEQK DKELYPSTAL KSLFGNDPLL
500
501
Q                                                     
501
 

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Checksums:
CRC64:827C2609BC3E5963
MD5:5430ac71aa49b1d1f4e58bcfbf492a12

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Gag_p24 167 - 179 1SJH C 34 - 46 Jmol AstexViewer SPICE
167 - 181 1SJE C 34 - 48 Jmol AstexViewer SPICE
Gag_p6 451 - 455 3D3T P 6 - 10 Jmol AstexViewer SPICE