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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: HN_NDVA (P12554)

Summary

This is the summary of UniProt entry HN_NDVA (P12554).

Description: Hemagglutinin-neuraminidase EC=3.2.1.18
Source organism: Newcastle disease virus (strain Chicken/Australia-Victoria/32) (NDV) (NCBI taxonomy ID 11177)
Length: 570 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
transmembrane n/a 23 46
Pfam A HN 24 568
disorder n/a 261 262
disorder n/a 330 331
disorder n/a 350 351
low_complexity n/a 508 521

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P12554. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNRAVCQVAL ENDEREAKNT WRLVFRIAIL LLTVMTLAIS AAALAYSMEA
50
51
STPGDLVSIP TAISRAEGKI TSALGSNQDV VDRIYKQVAL ESPLALLNTE
100
101
SIIMNAITSL SYQINGAANN SGCGAPVHDP DYIGGIGKEL IVDDTSDVTS
150
151
FYPSAFQEHL NFIPAPTTGS GCTRIPSFDM SATHCYTHNV IFSGCRDHSH
200
201
SHQYLALGVL RTSATGRVFF STLRSINLDD TQNRKSCSVS ATPLGCDMLC
250
251
SKVTETEEED YNSVIPTSMV HGRLGFDGQY HEKDLDVTTL FGDWVANYPG
300
301
VGGGSFIDNR VWFPVYGGLK PSSPSDTGQE GRYVIYKRYN DTCPDEQDYQ
350
351
IRMAKSSYKP GRFGGKRVQQ AILSIKVSTS LGEDPVLTIP PNTVTLMGAE
400
401
GRVLTVGTSH FLYQRGSSYF SPALLYPMTV NNNTATLHSP YTFNAFTRPG
450
451
SVPCQASARC PNSCVTGVYT DPYPLVFHRN HTLRGVFGTM LDDEQARLNL
500
501
VSAVFDNISR SRITRVSSSR TKAAYTTSTC FKVVKTNKTY CLSIAEISNT
550
551
LFGEFRIVPL LVEILKDDGV                                 
570
 

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Checksums:
CRC64:96EF3FFED67179D7
MD5:bdedde45e8dcc470bf2f0c01ccea0ad9

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
HN 123 - 568 3T1E A 123 - 568 Jmol AstexViewer SPICE
125 - 568 3T1E B 125 - 568 Jmol AstexViewer SPICE
79 - 115 3T1E E 79 - 115 Jmol AstexViewer SPICE
F 79 - 115 Jmol AstexViewer SPICE