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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: GBRA1_HUMAN (P14867)

Summary

This is the summary of UniProt entry GBRA1_HUMAN (P14867).

Description: Gamma-aminobutyric acid receptor subunit alpha-1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
View Pfam proteome data.
Length: 456 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 27
Pfam A Neur_chan_LBD 42 250
transmembrane n/a 250 274
Pfam A Neur_chan_memb 257 377
transmembrane n/a 281 300
transmembrane n/a 315 337
low_complexity n/a 347 364
Pfam A Neur_chan_memb 352 439
disorder n/a 373 374
low_complexity n/a 396 412
disorder n/a 397 413
transmembrane n/a 425 442
disorder n/a 449 456

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P14867. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MRKSPGLSDC LWAWILLLST LTGRSYGQPS LQDELKDNTT VFTRILDRLL
50
51
DGYDNRLRPG LGERVTEVKT DIFVTSFGPV SDHDMEYTID VFFRQSWKDE
100
101
RLKFKGPMTV LRLNNLMASK IWTPDTFFHN GKKSVAHNMT MPNKLLRITE
150
151
DGTLLYTMRL TVRAECPMHL EDFPMDAHAC PLKFGSYAYT RAEVVYEWTR
200
201
EPARSVVVAE DGSRLNQYDL LGQTVDSGIV QSSTGEYVVM TTHFHLKRKI
250
251
GYFVIQTYLP CIMTVILSQV SFWLNRESVP ARTVFGVTTV LTMTTLSISA
300
301
RNSLPKVAYA TAMDWFIAVC YAFVFSALIE FATVNYFTKR GYAWDGKSVV
350
351
PEKPKKVKDP LIKKNNTYAP TATSYTPNLA RGDPGLATIA KSATIEPKEV
400
401
KPETKPPEPK KTFNSVSKID RLSRIAFPLL FGIFNLVYWA TYLNREPQLK
450
451
APTPHQ                                                
456
 

Show the unformatted sequence.

Checksums:
CRC64:F81EC9ECBE64E94D
MD5:6f223d638083762b747dd3a626600088

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.