Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: T2F1_PLAOK (P14870)

Summary

This is the summary of UniProt entry T2F1_PLAOK (P14870).

Description: Type-2 restriction enzyme FokI EC=3.1.21.4
Source organism: Planomicrobium okeanokoites (Planococcus okeanokoites) (Flavobacterium okeanokoites) (NCBI taxonomy ID 244)
Length: 583 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam A FokI_N 1 147
Pfam A FokI_C 150 289
low_complexity n/a 387 406
Pfam A Endonuc-FokI_C 391 583
disorder n/a 490 492
disorder n/a 494 497

Show or hide domain scores.

Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

Note: it can take a few seconds for this image to be generated and loaded.

Loading feature alignment...

Show sources update panel.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P14870. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFLSMVSKIR TFGWVQNPGK FENLKRVVQV FDRNSKVHNE VKNIKIPTLV
50
51
KESKIQKELV AIMNQHDLIY TYKELVGTGT SIRSEAPCDA IIQATIADQG
100
101
NKKGYIDNWS SDGFLRWAHA LGFIEYINKS DSFVITDVGL AYSKSADGSA
150
151
IEKEILIEAI SSYPPAIRIL TLLEDGQHLT KFDLGKNLGF SGESGFTSLP
200
201
EGILLDTLAN AMPKDKGEIR NNWEGSSDKY ARMIGGWLDK LGLVKQGKKE
250
251
FIIPTLGKPD NKEFISHAFK ITGEGLKVLR RAKGSTKFTR VPKRVYWEML
300
301
ATNLTDKEYV RTRRALILEI LIKAGSLKIE QIQDNLKKLG FDEVIETIEN
350
351
DIKGLINTGI FIEIKGRFYQ LKDHILQFVI PNRGVTKQLV KSELEEKKSE
400
401
LRHKLKYVPH EYIELIEIAR NSTQDRILEM KVMEFFMKVY GYRGKHLGGS
450
451
RKPDGAIYTV GSPIDYGVIV DTKAYSGGYN LPIGQADEMQ RYVEENQTRN
500
501
KHINPNEWWK VYPSSVTEFK FLFVSGHFKG NYKAQLTRLN HITNCNGAVL
550
551
SVEELLIGGE MIKAGTLTLE EVRRKFNNGE INF                  
583
 

Show the unformatted sequence.

Checksums:
CRC64:F4AF13DEEFA5CF09
MD5:12f073e54c4636b31fe5e2add1922a09

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Endonuc-FokI_C 391 - 583 1FOK A 387 - 579 Jmol AstexViewer SPICE
2FOK A 387 - 579 Jmol AstexViewer SPICE
B 387 - 579 Jmol AstexViewer SPICE
FokI_C 150 - 285 1FOK A 146 - 281 Jmol AstexViewer SPICE
150 - 289 2FOK A 146 - 285 Jmol AstexViewer SPICE
B 146 - 285 Jmol AstexViewer SPICE
FokI_N 8 - 147 1FOK A 4 - 143 Jmol AstexViewer SPICE
9 - 147 2FOK A 5 - 143 Jmol AstexViewer SPICE
B 5 - 143 Jmol AstexViewer SPICE