Summary
This is the summary of UniProt entry ZNF8_HUMAN (P17098).
| Description: | Zinc finger protein 8 |
| Source organism: |
Homo sapiens (Human)
(NCBI taxonomy ID
9606)
View Pfam proteome data. |
| Length: | 575 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| disorder | n/a | 1 | 20 |
| disorder | n/a | 24 | 27 |
| Pfam A | KRAB | 25 | 65 |
| disorder | n/a | 32 | 36 |
| disorder | n/a | 45 | 46 |
| disorder | n/a | 61 | 62 |
| disorder | n/a | 69 | 82 |
| disorder | n/a | 84 | 86 |
| disorder | n/a | 88 | 150 |
| disorder | n/a | 154 | 156 |
| disorder | n/a | 159 | 165 |
| disorder | n/a | 168 | 170 |
| disorder | n/a | 185 | 189 |
| disorder | n/a | 194 | 200 |
| disorder | n/a | 202 | 205 |
| disorder | n/a | 210 | 240 |
| disorder | n/a | 245 | 247 |
| Pfam A | zf-H2C2_2 | 271 | 296 |
| disorder | n/a | 273 | 275 |
| Pfam A | zf-H2C2_2 | 299 | 322 |
| disorder | n/a | 301 | 303 |
| Pfam A | zf-H2C2_2 | 327 | 352 |
| Pfam A | zf-H2C2_2 | 355 | 380 |
| disorder | n/a | 357 | 359 |
| Pfam A | zf-H2C2_2 | 384 | 408 |
| disorder | n/a | 410 | 415 |
| disorder | n/a | 417 | 420 |
| disorder | n/a | 450 | 457 |
| disorder | n/a | 459 | 463 |
| Pfam A | zf-C2H2 | 467 | 489 |
| disorder | n/a | 485 | 544 |
| low_complexity | n/a | 498 | 510 |
| disorder | n/a | 550 | 559 |
| disorder | n/a | 567 | 571 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P17098. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MDPEDEGVAG VMSVGPPAAR LQEPVTFRDV AVDFTQEEWG QLDPTQRILY
50 51
RDVMLETFGH LLSIGPELPK PEVISQLEQG TELWVAERGT TQGCHPAWEP
100 101
RSESQASRKE EGLPEEEPSH VTGREGFPTD APYPTTLGKD RECQSQSLAL
150 151
KEQNNLKQLE FGLKEAPVQD QGYKTLRLRE NCVLSSSPNP FPEISRGEYL
200 201
YTYDSQITDS EHNSSLVSQQ TGSPGKQPGE NSDCHRDSSQ AIPITELTKS
250 251
QVQDKPYKCT DCGKSFNHNA HLTVHKRIHT GERPYMCKEC GKAFSQNSSL
300 301
VQHERIHTGD KPYKCAECGK SFCHSTHLTV HRRIHTGEKP YECQDCGRAF
350 351
NQNSSLGRHK RTHTGEKPYT CSVCGKSFSR TTCLFLHLRT HTEERPYECN
400 401
HCGKGFRHSS SLAQHQRKHA GEKPFECRQR LIFEQTPALT KHEWTEALGC
450 451
DPPLSQDERT HRSDRPFKCN QCGKCFIQSS HLIRHQITHT REEQPHGRSR
500 501
RREQSSSRNS HLVQHQHPNS RKSSAGGAKA GQPESRALAL FDIQKIMQEK
550 551
NPVHVIGVEE PSVGASMLFD IREST
575
Show the unformatted sequence. |
| Checksums: |
CRC64:E8F5B9C2FBED92C6
MD5:e98c4b1209afdc64b543fc8318af57ba
|
TreeFam
Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.