Summary
This is the summary of UniProt entry FAS2_YEAST (P19097).
| Description: | Fatty acid synthase subunit alpha Acyl carrier 3-oxoacyl-[acyl-carrier-protein] reductase 3-oxoacyl-[acyl-carrier-protein] synthase EC=2.3.1.86 EC=1.1.1.100 EC=2.3.1.41 |
| Source organism: |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
(NCBI taxonomy ID
559292)
View Pfam proteome data. |
| Length: | 1887 amino acids |
Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.
Pfam domains
| Source | Domain | Start | End |
|---|---|---|---|
| Pfam B | Pfam-B_4695 | 1 | 68 |
| Pfam B | Pfam-B_3273 | 70 | 423 |
| disorder | n/a | 92 | 126 |
| low_complexity | n/a | 98 | 163 |
| disorder | n/a | 187 | 211 |
| low_complexity | n/a | 196 | 212 |
| low_complexity | n/a | 225 | 235 |
| low_complexity | n/a | 303 | 321 |
| coiled_coil | n/a | 354 | 374 |
| disorder | n/a | 495 | 497 |
| disorder | n/a | 501 | 514 |
| disorder | n/a | 516 | 517 |
| disorder | n/a | 522 | 523 |
| disorder | n/a | 530 | 531 |
| disorder | n/a | 533 | 542 |
| disorder | n/a | 550 | 551 |
| disorder | n/a | 592 | 603 |
| disorder | n/a | 607 | 610 |
| disorder | n/a | 612 | 613 |
| disorder | n/a | 616 | 618 |
| low_complexity | n/a | 619 | 630 |
| Pfam A | adh_short_C2 | 682 | 931 |
| disorder | n/a | 1138 | 1140 |
| Pfam A | ketoacyl-synt | 1158 | 1393 |
| disorder | n/a | 1352 | 1374 |
| disorder | n/a | 1417 | 1427 |
| disorder | n/a | 1429 | 1431 |
| disorder | n/a | 1437 | 1440 |
| low_complexity | n/a | 1464 | 1476 |
| disorder | n/a | 1473 | 1474 |
| disorder | n/a | 1483 | 1492 |
| coiled_coil | n/a | 1487 | 1507 |
| Pfam A | Ketoacyl-synt_C | 1495 | 1612 |
| disorder | n/a | 1496 | 1501 |
| disorder | n/a | 1504 | 1507 |
| disorder | n/a | 1542 | 1545 |
| disorder | n/a | 1547 | 1563 |
| Pfam A | ACPS | 1768 | 1882 |
| disorder | n/a | 1851 | 1855 |
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Sequence annotations
This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...
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Sequence information
This is the amino acid sequence of the UniProt sequence database entry with the accession P19097. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.
| Sequence: | 1
MKPEVEQELA HILLTELLAY QFASPVRWIE TQDVFLKDFN TERVVEIGPS
50 51
PTLAGMAQRT LKNKYESYDA ALSLHREILC YSKDAKEIYY TPDPSELAAK
100 101
EEPAKEEAPA PTPAASAPAP AAAAPAPVAA AAPAAAAAEI ADEPVKASLL
150 151
LHVLVAHKLK KSLDSIPMSK TIKDLVGGKS TVQNEILGDL GKEFGTTPEK
200 201
PEETPLEELA ETFQDTFSGA LGKQSSSLLS RLISSKMPGG FTITVARKYL
250 251
QTRWGLPSGR QDGVLLVALS NEPAARLGSE ADAKAFLDSM AQKYASIVGV
300 301
DLSSAASASG AAGAGAAAGA AMIDAGALEE ITKDHKVLAR QQLQVLARYL
350 351
KMDLDNGERK FLKEKDTVAE LQAQLDYLNA ELGEFFVNGV ATSFSRKKAR
400 401
TFDSSWNWAK QSLLSLYFEI IHGVLKNVDR EVVSEAINIM NRSNDALIKF
450 451
MEYHISNTDE TKGENYQLVK TLGEQLIENC KQVLDVDPVY KDVAKPTGPK
500 501
TAIDKNGNIT YSEEPREKVR KLSQYVQEMA LGGPITKESQ PTIEEDLTRV
550 551
YKAISAQADK QDISSSTRVE FEKLYSDLMK FLESSKEIDP SQTTQLAGMD
600 601
VEDALDKDST KEVASLPNKS TISKTVSSTI PRETIPFLHL RKKTPAGDWK
650 651
YDRQLSSLFL DGLEKAAFNG VTFKDKYVLI TGAGKGSIGA EVLQGLLQGG
700 701
AKVVVTTSRF SKQVTDYYQS IYAKYGAKGS TLIVVPFNQG SKQDVEALIE
750 751
FIYDTEKNGG LGWDLDAIIP FAAIPEQGIE LEHIDSKSEF AHRIMLTNIL
800 801
RMMGCVKKQK SARGIETRPA QVILPMSPNH GTFGGDGMYS ESKLSLETLF
850 851
NRWHSESWAN QLTVCGAIIG WTRGTGLMSA NNIIAEGIEK MGVRTFSQKE
900 901
MAFNLLGLLT PEVVELCQKS PVMADLNGGL QFVPELKEFT AKLRKELVET
950 951
SEVRKAVSIE TALEHKVVNG NSADAAYAQV EIQPRANIQL DFPELKPYKQ
1000 1001
VKQIAPAELE GLLDLERVIV VTGFAEVGPW GSARTRWEME AFGEFSLEGC
1050 1051
VEMAWIMGFI SYHNGNLKGR PYTGWVDSKT KEPVDDKDVK AKYETSILEH
1100 1101
SGIRLIEPEL FNGYNPEKKE MIQEVIVEED LEPFEASKET AEQFKHQHGD
1150 1151
KVDIFEIPET GEYSVKLLKG ATLYIPKALR FDRLVAGQIP TGWNAKTYGI
1200 1201
SDDIISQVDP ITLFVLVSVV EAFIASGITD PYEMYKYVHV SEVGNCSGSG
1250 1251
MGGVSALRGM FKDRFKDEPV QNDILQESFI NTMSAWVNML LISSSGPIKT
1300 1301
PVGACATSVE SVDIGVETIL SGKARICIVG GYDDFQEEGS FEFGNMKATS
1350 1351
NTLEEFEHGR TPAEMSRPAT TTRNGFMEAQ GAGIQIIMQA DLALKMGVPI
1400 1401
YGIVAMAATA TDKIGRSVPA PGKGILTTAR EHHSSVKYAS PNLNMKYRKR
1450 1451
QLVTREAQIK DWVENELEAL KLEAEEIPSE DQNEFLLERT REIHNEAESQ
1500 1501
LRAAQQQWGN DFYKRDPRIA PLRGALATYG LTIDDLGVAS FHGTSTKAND
1550 1551
KNESATINEM MKHLGRSEGN PVIGVFQKFL TGHPKGAAGA WMMNGALQIL
1600 1601
NSGIIPGNRN ADNVDKILEQ FEYVLYPSKT LKTDGVRAVS ITSFGFGQKG
1650 1651
GQAIVVHPDY LYGAITEDRY NEYVAKVSAR EKSAYKFFHN GMIYNKLFVS
1700 1701
KEHAPYTDEL EEDVYLDPLA RVSKDKKSGS LTFNSKNIQS KDSYINANTI
1750 1751
ETAKMIENMT KEKVSNGGVG VDVELITSIN VENDTFIERN FTPQEIEYCS
1800 1801
AQPSVQSSFA GTWSAKEAVF KSLGVKSLGG GAALKDIEIV RVNKNAPAVE
1850 1851
LHGNAKKAAE EAGVTDVKVS ISHDDLQAVA VAVSTKK
1887
Show the unformatted sequence. |
| Checksums: |
CRC64:08B872734CF3AEEA
MD5:fcc42f04c35fe6079bc2d36b2f6de023
|
Structures
For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.