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5  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: FAS2_YEAST (P19097)

Summary

This is the summary of UniProt entry FAS2_YEAST (P19097).

Description: Fatty acid synthase subunit alpha Acyl carrier 3-oxoacyl-[acyl-carrier-protein] reductase 3-oxoacyl-[acyl-carrier-protein] synthase EC=2.3.1.86 EC=1.1.1.100 EC=2.3.1.41
Source organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (NCBI taxonomy ID 559292)
View Pfam proteome data.
Length: 1887 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
Pfam B Pfam-B_4695 1 68
Pfam B Pfam-B_3273 70 423
disorder n/a 92 126
low_complexity n/a 98 163
disorder n/a 187 211
low_complexity n/a 196 212
low_complexity n/a 225 235
low_complexity n/a 303 321
coiled_coil n/a 354 374
disorder n/a 495 497
disorder n/a 501 514
disorder n/a 516 517
disorder n/a 522 523
disorder n/a 530 531
disorder n/a 533 542
disorder n/a 550 551
disorder n/a 592 603
disorder n/a 607 610
disorder n/a 612 613
disorder n/a 616 618
low_complexity n/a 619 630
Pfam A adh_short_C2 682 931
disorder n/a 1138 1140
Pfam A ketoacyl-synt 1158 1393
disorder n/a 1352 1374
disorder n/a 1417 1427
disorder n/a 1429 1431
disorder n/a 1437 1440
low_complexity n/a 1464 1476
disorder n/a 1473 1474
disorder n/a 1483 1492
coiled_coil n/a 1487 1507
Pfam A Ketoacyl-synt_C 1495 1612
disorder n/a 1496 1501
disorder n/a 1504 1507
disorder n/a 1542 1545
disorder n/a 1547 1563
Pfam A ACPS 1768 1882
disorder n/a 1851 1855

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P19097. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKPEVEQELA HILLTELLAY QFASPVRWIE TQDVFLKDFN TERVVEIGPS
50
51
PTLAGMAQRT LKNKYESYDA ALSLHREILC YSKDAKEIYY TPDPSELAAK
100
101
EEPAKEEAPA PTPAASAPAP AAAAPAPVAA AAPAAAAAEI ADEPVKASLL
150
151
LHVLVAHKLK KSLDSIPMSK TIKDLVGGKS TVQNEILGDL GKEFGTTPEK
200
201
PEETPLEELA ETFQDTFSGA LGKQSSSLLS RLISSKMPGG FTITVARKYL
250
251
QTRWGLPSGR QDGVLLVALS NEPAARLGSE ADAKAFLDSM AQKYASIVGV
300
301
DLSSAASASG AAGAGAAAGA AMIDAGALEE ITKDHKVLAR QQLQVLARYL
350
351
KMDLDNGERK FLKEKDTVAE LQAQLDYLNA ELGEFFVNGV ATSFSRKKAR
400
401
TFDSSWNWAK QSLLSLYFEI IHGVLKNVDR EVVSEAINIM NRSNDALIKF
450
451
MEYHISNTDE TKGENYQLVK TLGEQLIENC KQVLDVDPVY KDVAKPTGPK
500
501
TAIDKNGNIT YSEEPREKVR KLSQYVQEMA LGGPITKESQ PTIEEDLTRV
550
551
YKAISAQADK QDISSSTRVE FEKLYSDLMK FLESSKEIDP SQTTQLAGMD
600
601
VEDALDKDST KEVASLPNKS TISKTVSSTI PRETIPFLHL RKKTPAGDWK
650
651
YDRQLSSLFL DGLEKAAFNG VTFKDKYVLI TGAGKGSIGA EVLQGLLQGG
700
701
AKVVVTTSRF SKQVTDYYQS IYAKYGAKGS TLIVVPFNQG SKQDVEALIE
750
751
FIYDTEKNGG LGWDLDAIIP FAAIPEQGIE LEHIDSKSEF AHRIMLTNIL
800
801
RMMGCVKKQK SARGIETRPA QVILPMSPNH GTFGGDGMYS ESKLSLETLF
850
851
NRWHSESWAN QLTVCGAIIG WTRGTGLMSA NNIIAEGIEK MGVRTFSQKE
900
901
MAFNLLGLLT PEVVELCQKS PVMADLNGGL QFVPELKEFT AKLRKELVET
950
951
SEVRKAVSIE TALEHKVVNG NSADAAYAQV EIQPRANIQL DFPELKPYKQ
1000
1001
VKQIAPAELE GLLDLERVIV VTGFAEVGPW GSARTRWEME AFGEFSLEGC
1050
1051
VEMAWIMGFI SYHNGNLKGR PYTGWVDSKT KEPVDDKDVK AKYETSILEH
1100
1101
SGIRLIEPEL FNGYNPEKKE MIQEVIVEED LEPFEASKET AEQFKHQHGD
1150
1151
KVDIFEIPET GEYSVKLLKG ATLYIPKALR FDRLVAGQIP TGWNAKTYGI
1200
1201
SDDIISQVDP ITLFVLVSVV EAFIASGITD PYEMYKYVHV SEVGNCSGSG
1250
1251
MGGVSALRGM FKDRFKDEPV QNDILQESFI NTMSAWVNML LISSSGPIKT
1300
1301
PVGACATSVE SVDIGVETIL SGKARICIVG GYDDFQEEGS FEFGNMKATS
1350
1351
NTLEEFEHGR TPAEMSRPAT TTRNGFMEAQ GAGIQIIMQA DLALKMGVPI
1400
1401
YGIVAMAATA TDKIGRSVPA PGKGILTTAR EHHSSVKYAS PNLNMKYRKR
1450
1451
QLVTREAQIK DWVENELEAL KLEAEEIPSE DQNEFLLERT REIHNEAESQ
1500
1501
LRAAQQQWGN DFYKRDPRIA PLRGALATYG LTIDDLGVAS FHGTSTKAND
1550
1551
KNESATINEM MKHLGRSEGN PVIGVFQKFL TGHPKGAAGA WMMNGALQIL
1600
1601
NSGIIPGNRN ADNVDKILEQ FEYVLYPSKT LKTDGVRAVS ITSFGFGQKG
1650
1651
GQAIVVHPDY LYGAITEDRY NEYVAKVSAR EKSAYKFFHN GMIYNKLFVS
1700
1701
KEHAPYTDEL EEDVYLDPLA RVSKDKKSGS LTFNSKNIQS KDSYINANTI
1750
1751
ETAKMIENMT KEKVSNGGVG VDVELITSIN VENDTFIERN FTPQEIEYCS
1800
1801
AQPSVQSSFA GTWSAKEAVF KSLGVKSLGG GAALKDIEIV RVNKNAPAVE
1850
1851
LHGNAKKAAE EAGVTDVKVS ISHDDLQAVA VAVSTKK              
1887
 

Show the unformatted sequence.

Checksums:
CRC64:08B872734CF3AEEA
MD5:fcc42f04c35fe6079bc2d36b2f6de023

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ACPS 1768 - 1882 2WAS A 1768 - 1882 Jmol AstexViewer SPICE
B 1768 - 1882 Jmol AstexViewer SPICE
C 1768 - 1882 Jmol AstexViewer SPICE
D 1768 - 1882 Jmol AstexViewer SPICE
E 1768 - 1882 Jmol AstexViewer SPICE
F 1768 - 1882 Jmol AstexViewer SPICE
2WAT A 1768 - 1882 Jmol AstexViewer SPICE
B 1768 - 1882 Jmol AstexViewer SPICE
C 1768 - 1882 Jmol AstexViewer SPICE
D 1768 - 1882 Jmol AstexViewer SPICE
E 1768 - 1882 Jmol AstexViewer SPICE
F 1768 - 1882 Jmol AstexViewer SPICE
3HMJ A 1768 - 1882 Jmol AstexViewer SPICE
B 1768 - 1882 Jmol AstexViewer SPICE
C 1768 - 1882 Jmol AstexViewer SPICE
adh_short_C2 682 - 931 2UV8 A 682 - 931 Jmol AstexViewer SPICE
B 682 - 931 Jmol AstexViewer SPICE
C 682 - 931 Jmol AstexViewer SPICE
2VKZ A 682 - 931 Jmol AstexViewer SPICE
B 682 - 931 Jmol AstexViewer SPICE
C 682 - 931 Jmol AstexViewer SPICE
3HMJ A 682 - 931 Jmol AstexViewer SPICE
B 682 - 931 Jmol AstexViewer SPICE
C 682 - 931 Jmol AstexViewer SPICE
ketoacyl-synt 1158 - 1393 2UV8 A 1158 - 1393 Jmol AstexViewer SPICE
B 1158 - 1393 Jmol AstexViewer SPICE
C 1158 - 1393 Jmol AstexViewer SPICE
2VKZ A 1158 - 1393 Jmol AstexViewer SPICE
B 1158 - 1393 Jmol AstexViewer SPICE
C 1158 - 1393 Jmol AstexViewer SPICE
3HMJ A 1158 - 1393 Jmol AstexViewer SPICE
B 1158 - 1393 Jmol AstexViewer SPICE
C 1158 - 1393 Jmol AstexViewer SPICE
Ketoacyl-synt_C 1495 - 1612 2UV8 A 1495 - 1612 Jmol AstexViewer SPICE
B 1495 - 1612 Jmol AstexViewer SPICE
C 1495 - 1612 Jmol AstexViewer SPICE
2VKZ A 1495 - 1612 Jmol AstexViewer SPICE
B 1495 - 1612 Jmol AstexViewer SPICE
C 1495 - 1612 Jmol AstexViewer SPICE
3HMJ A 1495 - 1612 Jmol AstexViewer SPICE
B 1495 - 1612 Jmol AstexViewer SPICE
C 1495 - 1612 Jmol AstexViewer SPICE