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2  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ALDH2_BOVIN (P20000)

Summary

This is the summary of UniProt entry ALDH2_BOVIN (P20000).

Description: Aldehyde dehydrogenase, mitochondrial EC=1.2.1.3
Source organism: Bos taurus (Bovine) (NCBI taxonomy ID 9913)
View Pfam proteome data.
Length: 520 amino acids

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Source Domain Start End
sig_p n/a 1 17
low_complexity n/a 2 12
disorder n/a 20 27
Pfam A Aldedh 48 511
low_complexity n/a 76 89
disorder n/a 352 362
low_complexity n/a 380 395

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Sequence annotations

This section shows a graphical representation of this sequence, with Pfam domains shown in the standard Pfam format. Under the Pfam domain image we show various tracks, illustrating features on this sequence that we found in other databases. You can choose which databases to include using the drop-down panel under the image. More...

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession P20000. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MLRAVALAAA RLGPRQGRRL LSAATQAVPT PNQQPEVLYN QIFINNEWHD
50
51
AVSKKTFPTV NPSTGDVICH VAEGDKADVD RAVKAARAAF QLGSPWRRMD
100
101
ASERGRLLNR LADLIERDRT YLAALETLDN GKPYIISYLV DLDMVLKCLR
150
151
YYAGWADKYH GKTIPIDGDY FSYTRHEPVG VCGQIIPWNF PLLMQAWKLG
200
201
PALATGNVVV MKVAEQTPLT ALYVANLIKE AGFPPGVVNV IPGFGPTAGA
250
251
AIASHEDVDK VAFTGSTEVG HLIQVAAGKS NLKRVTLELG GKSPNIIMSD
300
301
ADMDWAVEQA HFALFFNQGQ CCCAGSRTFV QEDIYAEFVE RSVARAKSRV
350
351
VGNPFDSRTE QGPQVDETQF KKVLGYIKSG KEEGAKLLCG GGAAADRGYF
400
401
IQPTVFGDVQ DGMTIAKEEI FGPVMQILKF KSMEEVVGRA NNSKYGLAAA
450
451
VFTKDLDKAN YLSQALQAGT VWVNCYDVFG AQSPFGGYKL SGSGRELGEY
500
501
GLQAYTEVKT VTVRVPQKNS                                 
520
 

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Checksums:
CRC64:713FC1EE8F82B2C4
MD5:c95bb819a26f48063a763178fc42ccf4

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the MSD group, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Aldedh 48 - 511 1A4Z A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE
1AG8 A 28 - 491 Jmol AstexViewer SPICE
B 28 - 491 Jmol AstexViewer SPICE
C 28 - 491 Jmol AstexViewer SPICE
D 28 - 491 Jmol AstexViewer SPICE

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.